Personalised Medicine

Lessons from Neurodegeneration to Cancer

  • Sherif El-Khamisy

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1007)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Anastasios Liakos, Matthieu D. Lavigne, Maria Fousteri
    Pages 17-39
  3. Walaa R. Allam, Mohamed E. Ashour, Amr A. Waly, Sherif El-Khamisy
    Pages 41-58
  4. Rana Alaaeddine, Mira Fayad, Eliana Nehme, Hisham F. Bahmad, Firas Kobeissy
    Pages 59-70
  5. Ahmed Maher, Mohamed F. Abdel Rahman, Mohamed Z. Gad
    Pages 71-88
  6. Guillaume M. Hautbergue
    Pages 89-109
  7. Chloe F. Allen, Pamela J. Shaw, Laura Ferraiuolo
    Pages 111-128
  8. Laila A. Selim, Heba Hassaan
    Pages 129-155
  9. Arwa A. Abugable, Dahlia A. Awwad, Dalia Fleifel, Mohamed M. Ali, Sherif El-Khamisy, Menattallah Elserafy
    Pages 157-178
  10. Sarah Baxendale, Freek van Eeden, Robert Wilkinson
    Pages 179-197
  11. Nicholas F. Blair, Thomas J. R. Frith, Ivana Barbaric
    Pages 225-239
  12. Jayanth S. Chandran, Joseph M. Scarrott, Pamela J. Shaw, Mimoun Azzouz
    Pages 241-257
  13. Back Matter
    Pages 259-260

About this book


The mammalian genome is constantly challenged by exogenous and endogenous threats. Although much is known about the mechanisms that maintain genome integrity, little is known about the applications of this knowledge to combat human disease. The past 20 years has witnessed extensive research and progress in this area and scientists started to design new therapies harnessing individual genetic differences among patients to combat degenerative disorders and cancer. We summarize these advancements and discuss perspectives for the future of personalized medicine.


Cancer DNA repair Degenerative disorders Genome instability Personalised Medicine

Editors and affiliations

  • Sherif El-Khamisy
    • 1
  1. 1.Krebs Institute and Sheffield Institute for Nucleic Acids, Department of Molecular Biology and Biotechnology, Firth CourtUniversity of SheffieldSheffieldUnited Kingdom

Bibliographic information

Industry Sectors
Health & Hospitals
Oncology & Hematology
Consumer Packaged Goods