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Rapid Cell Magnetisation Using Cationised Magnetoferritin

  • Sara¬†Correia Carreira

Part of the Springer Theses book series (Springer Theses)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Sara Correia Carreira
    Pages 1-44
  3. Sara Correia Carreira
    Pages 45-100
  4. Sara Correia Carreira
    Pages 111-123
  5. Sara Correia Carreira
    Pages 125-137
  6. Sara Correia Carreira
    Pages 151-153
  7. Back Matter
    Pages 155-166

About this book

Introduction

Bringing together nanoscience with stem cell and bacterial cell biology, this thesis is truly interdisciplinary in scope. It shows that the creation of superparamagnetic nanoparticles inside a protein coat, followed by chemical functionalisation of the protein surface, provides a novel methodology for cell magnetisation using incubation times as short as one minute. Crucially, stem cell proliferation and multi-lineage differentiation capacity is not impaired after labelling. Due to the unspecific labelling mechanism, this thesis also shows that the same magnetic protein nanoparticles can be used for rapid bacterial magnetisation. Thus, it is possible to magnetically capture and concentrate pathogens from clinical samples quickly and highly efficiently.

Keywords

Magnetic Nanoparticles Magnetoferritin Protein Modification Stem Cell Magnetization Magnetic capture of pathogens Magnetic Cell Separation Bacteria Isolation Bacteria Magnetisation Magnetic labelling of biological cells

Authors and affiliations

  • Sara¬†Correia Carreira
    • 1
  1. 1.School of Oral and Dental SciencesUniversity of Bristol BristolUnited Kingdom

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-60333-9
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Springer, Cham
  • eBook Packages Physics and Astronomy
  • Print ISBN 978-3-319-60332-2
  • Online ISBN 978-3-319-60333-9
  • Series Print ISSN 2190-5053
  • Series Online ISSN 2190-5061
  • Buy this book on publisher's site
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