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Genome Editing in Neurosciences

  • Book
  • Open Access
  • © 2017

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Overview

  • Highlights how genome editing is enabling breakthroughs in how we study the brain
  • Identifies a powerful method to understand and treat central nervous system disorders
  • Reveals system-level insight into how the nervous system develops and functions
  • Includes supplementary material: sn.pub/extras

Part of the book series: Research and Perspectives in Neurosciences (NEUROSCIENCE)

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Table of contents (10 chapters)

Keywords

About this book

This book is open access under a CC BY 4.0 license.

CRISPR-Cas9 is a rapid, efficient, versatile and relatively cheap method for dissecting the molecular pathways that are the basis of life, as well as for investigating and potentially rectifying faults in these pathways that result in disease.

This book reviews how CRISPR-Cas9 and other genome editing techniques are advancing our understanding of development and function in the nervous system, uncovering the molecular causes of neurological disorders and providing tools for gene therapy.

Editors and Affiliations

  • Whitehead Institute and Department of Biology, Massachusetts Institute of Technology, Cambridge, USA

    Rudolf Jaenisch

  • Department of Brain and Cognitive Science, Broad Institute of MIT and Harvard, Cambridge, USA

    Feng Zhang

  • Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, USA

    Fred Gage

About the editors

Rudolf Jaenisch, MIT Cambridge, USAFeng Zhang, MIT Cambridge, USA
Fred Gage, Salk Institute for Biological Studies, La Jolla, CA, USA

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