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Development of the Cerebellum from Molecular Aspects to Diseases

  • Hassan Marzban
Book

Part of the Contemporary Clinical Neuroscience book series (CCNE)

Table of contents

  1. Front Matter
    Pages i-ix
    PDF
  2. The Development of the Cerebellum: From the Beginnings
    Jan Voogd
    Pages 1-32
  3. The Embryology and Anatomy of the Cerebellum
    Maryam Rahimi Balaei, Niloufar Ashtari, Hugo Bergen
    Pages 33-43
  4. Cellular and Genetic Programs Underlying Cerebellum Development
    Alexandra L. Joyner, Ryan Willett, Andrew Lawton
    Pages 45-65
  5. Early Purkinje Cell Development and the Origins of Cerebellar Patterning
    Filippo Casoni, Laura Croci, Ottavio Cremona, Richard Hawkes, G. Giacomo Consalez
    Pages 67-86
  6. Cerebellar Developmental Disorders and Cerebellar Nuclei
    Hong-Ting Prekop, Alessio Delogu, Richard J. T. Wingate
    Pages 87-104
  7. Motor Circuit Abnormalities During Cerebellar Development
    Elizabeth P. Lackey, Roy V. Sillitoe
    Pages 105-127
  8. Developmental Disorders of the Cerebellum and Neurotrophic Factors
    Leila Pirmoradi, Ali Akbar Owji, Shahla Shojaei
    Pages 129-151
  9. Apoptosis, Autophagy, and Unfolded Protein Response and Cerebellar Development
    Mohammad Amin Moosavi, Marveh Rahmati, Niloufar Ashtari, Javad Alizadeh, Mohammad Hashemi, Seyedeh Zahra Bathaei et al.
    Pages 153-178
  10. The Ubiquitin Proteasome System and Cerebellar Developmental Disease
    Jerry Vriend, Xiaodan Jiao
    Pages 179-196
  11. Epigenetics and Cerebellar Neurodevelopmental Disorders
    Mojgan Rastegar
    Pages 197-218
  12. Hormonal Regulation of Cerebellar Development and Its Disorders
    Noriyuki Koibuchi
    Pages 219-235
  13. Infections of the Cerebellum
    Kevin M. Coombs
    Pages 237-253
  14. Neuroimmune Mechanisms of Cerebellar Development and Its Developmental Disorders: Bidirectional Link Between the Immune System and Nervous System
    Nour Eissa, Laëtitia Kermarrec, Jean-Eric Ghia
    Pages 255-274
  15. Teratogenic Influences on Cerebellar Development
    Albert E. Chudley
    Pages 275-300
  16. Primary Pediatric Brain Tumors of the Posterior Fossa: Part I
    Kathleen Felton, Amanda Hogg, Lisa Liang, Christopher Aiken, Thomas Klonisch, Frank van Landeghem et al.
    Pages 301-326
  17. Primary Pediatric Brain Tumors of the Posterior Fossa Part II: A Comprehensive Overview of Medulloblastoma
    Lisa Liang, Christopher Aiken, Kathleen Felton, Amanda Hogg, Frank van Landeghem, T. Klonisch et al.
    Pages 327-351
  18. Can Cerebellar Neurodevelopmental Disorders Affect Behavioral Disorders or Vice Versa?
    Seyed Soheil Saeedi Saravi, Ahmad Reza Dehpour
    Pages 353-367
  19. Neurodevelopmental Disorders of the Cerebellum: Autism Spectrum Disorder
    Mehnosh Toback, Kambiz Zangeneh, Tabrez J. Siddiqui, Hassan Marzban
    Pages 369-387
  20. Clinical Aspects of the Inherited Cerebellar Malformations
    Asghar Marzban, Mohammad Vafaee-shahi, Kamran Azarkhish
    Pages 389-406
  21. Clinical Features, Assessment, and Management of Patients with Developmental and Other Cerebellar Disorders
    Michael S. Salman
    Pages 407-421
  22. Epidemiology of Cerebellar Disorders
    S. Shooshtari, B. M. Stoesz, P. Rad, S. Khoeiniha
    Pages 423-463
  23. Cerebellar Transplantation: A Potential Model to Study Repair and Development of Neurons and Circuits in the Cerebellum
    Constantino Sotelo
    Pages 465-493
  24. Correction to: Primary Pediatric Brain Tumors of the Posterior Fossa Part II: A Comprehensive Overview of Medulloblastoma
    Lisa Liang, Christopher Aiken, Kathleen Felton, Amanda Hogg, Frank van Landeghem, T. Klonisch et al.
    Pages C1-C1
    PDF
  25. Back Matter
    Pages 495-505
    PDF

About this book

Introduction

The authors present the most current and cutting-edge knowledge regarding the molecular basis of cerebellar development, focusing on information relevant to laboratory scientists and clinicians providing service to patients with cerebellar disorders. Knowledge obtained from advanced neuroimaging techniques that are used during development, and from molecular- and genetic-based studies has provided rapidly-growing evidence that the cerebellum is a brain region that is highly impacted by developmental defects. Cerebellar defects result in significant intellectual and motor function impairment that affects both the patients and their families.

Keywords

cerebellum cerebellar growth and development neurological disorder diagnosis management

Editors and affiliations

  • Hassan Marzban
    • 1
  1. 1.Department of Human Anatomy and Cell Science, The Children’s Hospital Research Institute of Manitoba (CHRIM), Max Rady College of Medicine, Rady Faculty of Health ScienceUniversity of ManitobaWinnipegCanada

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