Progress in the Chemistry of Organic Natural Products 106

  • A. Douglas Kinghorn
  • Heinz Falk
  • Simon Gibbons
  • Jun'ichi Kobayashi

Part of the Progress in the Chemistry of Organic Natural Products book series (POGRCHEM, volume 106)

Table of contents

  1. Front Matter
    Pages i-v
  2. He-Ping Chen, Ji-Kai Liu
    Pages 1-201
  3. Satyajit D. Sarker, Lutfun Nahar
    Pages 241-304

About this book


The first contribution presents coumarins, the largest group of 1-benzopyran derivatives found in plants. Coumarin chemistry remains one of the major interest areas of phytochemists, especially because of their structural diversity and medicinal properties, along with the wide-ranging bioactivities of these compounds, inclusive of analgesic, anticoagulant anti-HIV, anti-inflammatory, antimicrobial, antineoplastic, antioxidant, and immunomodulatory effects. The second contribution presents a comprehensive survey of the many aspects of PAD biochemistry and physiology. The third contribution gives a comprehensive overview of secondary metabolites from higher fungi, with more than 700 references highlighting the isolation, structure elucidation, biological activities, chemical synthesis, and biosynthesis of pigments, nitrogen-containing compounds, and terpenoids from mushrooms. 


Coumarins Secondary metabolites Biosynthesis Simple coumarins Peptidylarginine deiminase (PAD) enzymes Autoimmune diseases Neurodegeneration Higher fungi terpenoids from mushrooms Nitrogen-containing compounds

Editors and affiliations

  • A. Douglas Kinghorn
    • 1
  • Heinz Falk
    • 2
  • Simon Gibbons
    • 3
  • Jun'ichi Kobayashi
    • 4
  1. 1.Division of Medicinal Chemistry & Pharmacognosy, College of PharmacyThe Ohio State UniversityColumbusUSA
  2. 2.Institute of Organic ChemistryJohannes Kepler University LinzLinzAustria
  3. 3.Research Department of Pharmaceutical and Biological ChemistryUCL School of PharmacyLondonUnited Kingdom
  4. 4.Graduate School of Pharmaceutical ScienceHokkaido UniversitySapporoJapan

Bibliographic information

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