Behavioral Neuroscience of Orexin/Hypocretin

  • Andrew J Lawrence
  • Luis de Lecea

Part of the Current Topics in Behavioral Neurosciences book series (CTBN, volume 33)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Jie Yin, Daniel M. Rosenbaum
    Pages 1-15
  3. Jyrki P. Kukkonen
    Pages 17-50
  4. Idan Elbaz, Talia Levitas-Djerbi, Lior Appelbaum
    Pages 75-92
  5. Shi-Bin Li, William J. Giardino, Luis de Lecea
    Pages 93-104
  6. Laura H. Jacobson, Sui Chen, Sanjida Mir, Daniel Hoyer
    Pages 105-136
  7. Paulette B. Goforth, Martin G. Myers
    Pages 137-156
  8. Pascal Carrive, Tomoyuki Kuwaki
    Pages 157-196
  9. Morgan H. James, Erin J. Campbell, Christopher V. Dayas
    Pages 197-219
  10. Leigh C. Walker, Andrew J. Lawrence
    Pages 221-246
  11. Morgan H. James, Stephen V. Mahler, David E. Moorman, Gary Aston-Jones
    Pages 247-281
  12. Corey Baimel, Stephanie L. Borgland
    Pages 283-304
  13. Claudio Liguori
    Pages 305-322

About this book


This issue of Current Topics in Behavioral Neuroscience focuses on the neuropeptide orexin (hypocretin) and brings together scientists from around the world who will provide a timely discussion of how this peptide regulates behavior. This is a fast-moving field, and with the incorporation of novel technologies, new breakthroughs are likely to continue. For example, the use of optogenetic approaches has enabled the identification of the role of orexin-containing neurons in arousal states, critical for higher order functioning. From a clinical perspective, genetic polymorphisms in hypocretin/orexin and orexin receptors are implicated in a number of psychiatric disorders. In addition, advanced clinical trials are currently underway for orexin receptor antagonists in the treatment of insomnia and sleep disorders. We aim to capture a broad audience of basic scientists and clinicians.


orexin/hypocretin arousal addiction sleep pain panic neurodegeneration

Editors and affiliations

  • Andrew J Lawrence
    • 1
  • Luis de Lecea
    • 2
  1. 1.Florey Institute of Neuroscience & Mental Health, Melbourne Brain CentreUniversity of MelbourneParkvilleAustralia
  2. 2.Dep Psychiatry & Behav SciencesStanford UniversityStanfordUSA

Bibliographic information

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