Neurodegenerative Diseases

Pathology, Mechanisms, and Potential Therapeutic Targets

  • Philip Beart
  • Michael Robinson
  • Marcus Rattray
  • Nicholas J. Maragakis

Part of the Advances in Neurobiology book series (NEUROBIOL, volume 15)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Major Neurodegenerative Conditions

    1. Front Matter
      Pages 1-1
    2. Fiona Kumfor, Glenda M. Halliday, Olivier Piguet
      Pages 31-53
    3. Alastair Noyce, Rina Bandopadhyay
      Pages 55-92
    4. Dean J. Wright, Thibault Renoir, Laura J. Gray, Anthony J. Hannan
      Pages 93-128
    5. Lynette J. Tippett, Henry J. Waldvogel, Russell G. Snell, Jean-Paul Vonsattel, Anne B. Young, Richard L. M. Faull
      Pages 129-161
    6. Hristelina Ilieva, Nicholas J. Maragakis
      Pages 163-190
    7. Hristelina Ilieva, Nicholas J. Maragakis
      Pages 191-210
    8. Katherine Buzzard, Wing Hei Chan, Trevor Kilpatrick, Simon Murray
      Pages 211-252
  3. Other Neurological Conditions

    1. Front Matter
      Pages 253-253
    2. Joseph T. Coyle
      Pages 255-280
    3. Tarvinder P. Singh, Jonathan R. Weinstein, Sean P. Murphy
      Pages 281-293
    4. Ingo Helbig, Markus von Deimling, Eric D. Marsh
      Pages 295-315
    5. Jordan S. Farrell, Marshal D. Wolff, G. Campbell Teskey
      Pages 317-334
    6. Benjamin C. Whitechurch, Jeremy M. Welton, Steven J. Collins, Victoria A. Lawson
      Pages 335-364
    7. Gerald V. Raymond
      Pages 365-382
    8. Victoria E. Johnson, William Stewart, John D. Arena, Douglas H. Smith
      Pages 383-400
  4. Key Background and Key Technologies

    1. Front Matter
      Pages 401-401
    2. Jing Fan, Ted M. Dawson, Valina L. Dawson
      Pages 403-425
    3. Alexei Verkhratsky, Robert Zorec, J. J. Rodriguez, Vladimir Parpura
      Pages 427-449
    4. Michele Veldsman, Natalia Egorova
      Pages 451-478
    5. Mark R. Cookson
      Pages 479-489
    6. Andreas Jeromin, Robert Bowser
      Pages 491-528
  5. Philip Beart, Michael Robinson, Marcus Rattray, Nicholas J. Maragakis
    Pages E1-E1
  6. Back Matter
    Pages 529-542

About this book


Provides a timely overview of critical advances in molecular and cellular neurobiology, covers key methodologies driving progress, and highlights key future directions for research on neuronal injury and neurodegeneration relevant to neuronal brain pathologies. The editors bring together contributions from internationally recognized workers in the field to provide an up to date account of how and why molecular and cellular neurobiology is such an important area for clinical neuroscience. Understanding the molecular aspects of a number of neurodegenerative conditions such as Parkinson's or Alzheimer's disease for the purpose of improving patient management remains a major challenge of neurobiology be it from the basic or clinical perspective. A strategic evaluation of research contributions and the power of modern methods will help advance knowledge over the next years.


clinical neuroscience disease biomarkers molecular and cellular neurobiology neurodegeneration neuropathologies therapeutic targets

Editors and affiliations

  • Philip Beart
    • 1
  • Michael Robinson
    • 2
  • Marcus Rattray
    • 3
  • Nicholas J. Maragakis
    • 4
  1. 1.University of Melbourne Florey Institute of Neuroscience and Mental HealthParkvilleAustralia
  2. 2.Pediatrics and Pharmacology Children’s Hospital of PhiladelphiaUniversity of PennsylvaniaPhiladelphiaUSA
  3. 3.School of Life Sciences Bradford School of PharmacyUniversity of BradfordBradfordUnited Kingdom
  4. 4.Department of NeurologyJohns Hopkins University School of MedicineBaltimoreUSA

Bibliographic information

Industry Sectors
Health & Hospitals