Cell Division Machinery and Disease

  • Monica Gotta
  • Patrick Meraldi

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1002)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Warif El Yakoubi, Katja Wassmann
    Pages 1-17
  3. Maddalena Nano, Renata Basto
    Pages 19-45
  4. Alexander D. Rhys, Susana A. Godinho
    Pages 47-67
  5. Bas de Wolf, Geert J. P. L. Kops
    Pages 69-91
  6. Luca Cirillo, Monica Gotta, Patrick Meraldi
    Pages 93-124
  7. Anna-Maria Olziersky, S. Intidhar Labidi-Galy
    Pages 125-152
  8. Joana Catarina Macedo, Sara Vaz, Elsa Logarinho
    Pages 153-188
  9. Michael Polymenis, Brian K. Kennedy
    Pages 189-208
  10. Back Matter
    Pages 227-235

About this book


This book critically evaluates the causal link between cell division machinery and disease. Further, it identifies key open questions in the field and the means for exploring them. Throughout the various chapters, internationally known contributors present the evidence for and against a causal link between key elements of the cell division machinery and diseases such as cancer, neuropathologies, aging, and infertility. A more clinically oriented chapter further discusses the current and future applications of anti-mitotic drugs in these diseases. Cell Division Machinery and Disease is essential reading for graduate or advanced graduate students, researchers or scientists working on cell division as well as clinicians interested in the molecular mechanisms of the discussed diseases.


Centrosomes Infertility Mitosis Neuropathology Polycystic Kidney Disease

Editors and affiliations

  • Monica Gotta
    • 1
  • Patrick Meraldi
    • 2
  1. 1.Department of Cell Physiology and MetabolismFaculty of Medicine, Geneva UniversityGenevaSwitzerland
  2. 2.Department of Cell Physiology and MetabolismFaculty of Medicine, Geneva UniversityGenevaSwitzerland

Bibliographic information