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mGLU Receptors

  • Richard Teke Ngomba
  • Giuseppe Di Giovanni
  • Giuseppe Battaglia
  • Ferdinando Nicoletti

Part of the The Receptors book series (REC, volume 31)

Table of contents

  1. Front Matter
    Pages i-x
  2. Christina J. Perry, M. Foster Olive, Andrew J. Lawrence
    Pages 1-14
  3. Francesca Guida, Enza Palazzo, Livio Luongo, Ida Marabese, Vito de Novellis, Sabatino Maione et al.
    Pages 15-31
  4. Paolo Gubellini, Liliya Iskhakova, Yoland Smith, Marianne Amalric
    Pages 33-57
  5. Philippe Rondard, Xavier Rovira, Cyril Goudet, Jean-Philippe Pin
    Pages 129-147
  6. Thomas E. Salt, Caroline S. Copeland
    Pages 149-159
  7. Lumeng J. Yu, Brian A. Wall, Janet Wangari-Talbot, Suzie Chen
    Pages 161-182
  8. Gilles van Luijtelaar, Valerio D’Amore, Ines Santolini, Richard T. Ngomba
    Pages 207-224
  9. Francesco Ferraguti
    Pages 241-277
  10. Back Matter
    Pages 279-282

About this book

Introduction

Metabotropic glutamate receptors (mGluRs) are members of the group C family of G-protein-coupled receptors. Eight different mGlu subtypes have been identified and classified into three groups based on amino acid sequence similarity, agonist pharmacology, and the signal transduction pathways to which they couple. They perform a variety of functions in the central and peripheral nervous systems, being involved in learning, memory, anxiety, and the perception of pain. They are found in pre- and postsynaptic neurons in synapses of the hippocampus, cerebellum, and cerebral cortex, as well as other parts of the brain and peripheral tissues. This volume comprises the latest contributions of experts in the field on the role of mGlu receptor in health and disease, following the 8th International meeting on these receptors.

Keywords

Group I mGLU central nervous system mGLU receptors peripheral nervous system postsynaptic NMDA receptor excitotoxicity PDZ proteins Phospholipase C

Editors and affiliations

  • Richard Teke Ngomba
    • 1
  • Giuseppe Di Giovanni
    • 2
  • Giuseppe Battaglia
    • 3
  • Ferdinando Nicoletti
    • 4
  1. 1.Neuropharmacology Unit I.N.M. NeuromedI.N.M. NeuromedPozzilliItaly
  2. 2.Department of Physiology and BiochemistryUniversity of MaltaMaltaItaly
  3. 3.Neuropharmacology UnitI.N.M. NeuromedPozzilliItaly
  4. 4.Dipartimento di Fisiologia UmanaUniversità di RomaRomaItaly

Bibliographic information

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