About this book
This book provides a comprehensive, state-of-the-art review of PDX cancer models. In separately produced chapters, the history and evolution of PDX models is reviewed, methods of PDX model development are compared in detail, characteristics of available established models are presented, current applications are summarized and new perspectives about use of PDX models are proposed. Each chapter is written by a world-renowned expert who is conducting cutting-edge research in the field. Each of the subsections provide a comprehensive review of existing literature addressing the particular topic followed by a conclusive paragraph detailing future directions. Extensive illustrations make this an interactive text.
Patient-Derived Xenograft Models of Human Cancer will serve as a highly useful resource for researchers and clinicians dealing with, or interested in, this important topic. It will provide a concise yet comprehensive summary of the current status of the field that will help guide preclinical and clinical applications as well as stimulate investigative efforts. This book will propagate innovative concepts and prompt the development of ground-breaking technological solutions in this field.
PDX cancer models cancer heterogeneity Modeling cancer metastasis Modeling drug resistance PDX and biomarker development
Editors and affiliations
- DOI https://doi.org/10.1007/978-3-319-55825-7
- Copyright Information Springer International Publishing AG 2017
- Publisher Name Humana Press, Cham
- eBook Packages Medicine
- Print ISBN 978-3-319-55824-0
- Online ISBN 978-3-319-55825-7
- Series Print ISSN 2197-7852
- Series Online ISSN 2197-7860
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