© 2017

Oxygen Transport to Tissue XXXIX

  • Howard J. Halpern
  • Joseph C. LaManna
  • David K. Harrison
  • Boris Epel

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 977)

Table of contents

  1. Front Matter
    Pages i-xxx
  2. Cell Metabolism, Tissue Oxygenation and Treatment

    1. Front Matter
      Pages 1-1
    2. Nanduri R. Prabhakar, Ying-Jie Peng
      Pages 3-8
    3. Gary Angles, Rachel Dotson, Kristina Bueche, Sally C. Pias
      Pages 9-14
    4. Shun Takagi, Ryotaro Kime, Norio Murase, Masatsugu Niwayama, Takuya Osada, Toshihito Katsumura
      Pages 35-41
    5. Shun Takagi, Ryotaro Kime, Masatsugu Niwayama, Kuniaki Hirayama, Shizuo Sakamoto
      Pages 43-49
    6. Lily Moon, David W. Frederick, Joseph A. Baur, Lin Z. Li
      Pages 51-57
    7. Liangjie Yin, Lauren Vaught, Paul Okunieff, Katherine Casey-Sawicki, Sadasivan Vidyasagar
      Pages 59-65
    8. Rong-Wen Tain, Alessandro M. Scotti, Weiguo Li, Xiaohong Joe Zhou, Kejia Cai
      Pages 73-79
    9. Yudai Yamazaki, Daisuke Sato, Koya Yamashiro, Atsuhiro Tsubaki, Yui Yamaguchi, Nana Takehara et al.
      Pages 81-88
  3. Cancer Oxygenation and Metabolism

  4. Brain Oxygenation and Function

    1. Front Matter
      Pages 125-125

About this book


Chapters 10 and 19 of this book are open access under a CC BY 4.0 license.


Molecular oxygen Oxygen metabolism Oxygen transport Perfusion Blood substitutes Tumor hypoxia Hypoxia Cerebral oxygenation Sports medicine Oxygen measurement Oxygen imaging Electron paramagnetic resonance Electron paramagnetic resonance oxygen imaging Metabolic imaging Hypoxia signaling Retinal oxygenation

Editors and affiliations

  • Howard J. Halpern
    • 1
  • Joseph C. LaManna
    • 2
  • David K. Harrison
    • 3
  • Boris Epel
    • 4
  1. 1.Department of Radiation and Cellular Oncology, Center for EPR Imaging In Vivo PhysiologyUniversity of ChicagoChicagoUSA
  2. 2.Department of Physiology and BiophysicsCase Western Reserve University School of MedicineClevelandUSA
  3. 3.Microvascular MeasurementsSt. LorenzenItaly
  4. 4.Department of Radiation and Cellular Oncology, Center for EPR Imaging In Vivo PhysiologyUniversity of ChicagoChicagoUSA

About the editors

Howard J. Halpern  is Professor of Radiation and Cellular Oncology at the University of Chicago and Director, NIH Center for Electron Paramagnetic Resonance (EPR) Imaging In Vivo Physiology.  Dr. Halpern is both a physicist, supporting a graduate student as a member of the Committee of Medical Physics and a physician training Radiation Oncology residents.  His principle research focus is the application of EPR imaging for near absolute pO2 image formation.

Joseph C. LaManna is the Jeanette M. and Joseph S. Silber Professor of Brain Sciences at the Case Western Reserve University School of Medicine, Department of Physiology & Biophysics. He is the former chair of the Department of Anatomy at CWRU.  He is a Past President of The Federation of American Societies for Experimental Biology (FASEB), and Secretary of the International Society for Cerebral Blood Blow and Metabolism. He has published over 250 papers on the topic of oxygen and energy metabolism, especially in the field of brain blood flow and metabolism. He has been a member of the International Society for Oxygen Transport to Tissue since 1976, serving as President of the ISOTT in 2009. In 2016 he became the editor in Chief of the ISOTT proceedings.

David Harrison is CEO of Microvascular Measurements and acts as honorary Senior Scientific Consultant for Oroboros Instruments (Innsbruck, Austria). In this capacity he has recently been responsible for the development of lightguide spectrophotometry for the continuous measurement of cytochrome redox state in mitochondria during high resolution respirometry. Prior to this, he was Head of the Durham Unit of the Regional Medical Physics Department and Honorary Senior Lecturer in Medical Physics, Institute of Cellular Medicine, Newcastle University, UK until retiring from the NHS in 2009. He is author or co-author of over 130 publications, mainly in the field of blood flow and oxygen transport to tissue. He has been a member of ISOTT for over 30 years including being President in 1996. Since 2004 he has been Scientific Editor of the “Oxygen Transport to Tissue” volumes.

 Boris Epel was awarded his Ph.D. in physics in Kazan Federal University, Russia in 1999. He did his post-doctoral training in Weizmann Institute of Science, Israel and in the Max-Plank Institute for Bioinorganic Chemistry. Currently Boris Epel is a Research Professor in the Department of Radiation and Cellular Oncology and scientific manager of the Center for EPR imaging in vivo Physiology. The major focus of research is application of in vivo oxygen imaging to the improved radiation treatment of cancer. Boris Epel has been a member of the International Society for Oxygen Transport to Tissue since 2015.​

Bibliographic information

  • Book Title Oxygen Transport to Tissue XXXIX
  • Editors Howard J. Halpern
    Joseph C. LaManna
    David K. Harrison
    Boris Epel
  • Series Title Advances in Experimental Medicine and Biology
  • Series Abbreviated Title Adv Exp Med Biol
  • DOI
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-3-319-55229-3
  • Softcover ISBN 978-3-319-85601-8
  • eBook ISBN 978-3-319-55231-6
  • Series ISSN 0065-2598
  • Series E-ISSN 2214-8019
  • Edition Number 1
  • Number of Pages XXX, 435
  • Number of Illustrations 72 b/w illustrations, 64 illustrations in colour
  • Topics Biomedicine, general
  • Buy this book on publisher's site
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