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© 2017

Computational Methods for Processing and Analysis of Biological Pathways

Book

Part of the SpringerBriefs in Computer Science book series (BRIEFSCOMPUTER)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Anastasios Bezerianos, Andrei Dragomir, Panos Balomenos
    Pages 1-10
  3. Anastasios Bezerianos, Andrei Dragomir, Panos Balomenos
    Pages 11-46
  4. Anastasios Bezerianos, Andrei Dragomir, Panos Balomenos
    Pages 47-68
  5. Anastasios Bezerianos, Andrei Dragomir, Panos Balomenos
    Pages 69-87

About this book

Introduction

This work offers a guided walkthrough of one of the most promising research areas in modern life sciences, enabling a deeper understanding of involved concepts and methodologies via an interdisciplinary view, focusing on both well-established approaches and cutting-edge research. Highlighting what pathway analysis can offer to both the experimentalist and the modeler, the text opens with an introduction to a general methodology that outlines common workflows shared by several methods. This is followed by a review of pathway and sub-pathway based approaches for systems pharmacology. The work then presents an overview of pathway analysis methods developed to model the temporal aspects of drug- or disease-induced perturbations and extract relevant dynamic themes. The text concludes by discussing several state-of-the-art methods in pathway analysis, which address the important problem of identifying differentially expressed pathways and sub-pathways.

Keywords

Bioinformatics Systems Biology Network Biology Pathway Analysis Graph Theory

Authors and affiliations

  1. 1.University of PatrasPatrasGreece
  2. 2.University of HoustonHoustonUSA
  3. 3.University of PatrasPatrasGreece

About the authors

Anastasios Bezerianos is a Professor at the Medical School of Patras University, Greece. He is also a Senior Principal Research Fellow at the Singapore Institute for Neurotechnology (SINAPSE) within the Centre for Life Sciences (CeLS), a Research Professor in the Department of Electrical and Computer Engineering (ECE), and a member of the Faculty of NUS Graduate School (NGS) for Integrative Sciences and Engineering at the National University of Singapore (NUS).

Andrei Dragomir is a Research Assistant Professor at the Department of Biomedical Engineering of the University of Houston, TX, USA.

Panos Balomenos is a PhD Candidate at the Computer Engineering and Informatics Department of the University of Patras, Greece.

Bibliographic information

  • Book Title Computational Methods for Processing and Analysis of Biological Pathways
  • Authors Anastasios Bezerianos
    Andrei Dragomir
    Panos Balomenos
  • Series Title SpringerBriefs in Computer Science
  • Series Abbreviated Title SpringerBriefs Computer Sci.
  • DOI https://doi.org/10.1007/978-3-319-53868-6
  • Copyright Information The Author(s) 2017
  • Publisher Name Springer, Cham
  • eBook Packages Computer Science Computer Science (R0)
  • Softcover ISBN 978-3-319-53867-9
  • eBook ISBN 978-3-319-53868-6
  • Series ISSN 2191-5768
  • Series E-ISSN 2191-5776
  • Edition Number 1
  • Number of Pages VIII, 87
  • Number of Illustrations 0 b/w illustrations, 11 illustrations in colour
  • Topics Computational Biology/Bioinformatics
    Systems Biology
  • Buy this book on publisher's site
Industry Sectors
Biotechnology
Pharma