Pathogenesis of Periodontal Diseases

Biological Concepts for Clinicians

  • Nagihan Bostanci
  • Georgios N. Belibasakis

Table of contents

  1. Front Matter
    Pages i-v
  2. Nagihan Bostanci, Georgios N. Belibasakis
    Pages 1-7
  3. Thomas Thurnheer, Kai Bao, Georgios N. Belibasakis
    Pages 21-29
  4. Timo Sorsa, Anna Maria Heikkinen, Jussi Leppilahti, Taina Tervahartiala, Solomon Nwhator, Nilminie Rathnayake et al.
    Pages 51-57
  5. Franco Cavalla, Claudia C. Biguetti, Thiago P. Garlet, Ana Paula F. Trombone, Gustavo P. Garlet
    Pages 59-85
  6. Georgios N. Belibasakis, Nagihan Bostanci
    Pages 111-114

About this book


This book aims to provide clinicians with a refined understanding of the biology that underlies periodontal diseases, thereby offering a sound basis for improved clinical decision making with regard to prevention strategies, diagnosis, and therapy. All significant aspects of periodontal pathogenesis are covered, including the roles played by the oral microbiome and biofilms, bacterial virulence factors, cells of the immune system, matrix metalloproteinases, proinflammatory and osteolytic cytokines, genetic factors, and antimicrobial peptides.

Periodontal diseases are among the most common infectious diseases in humans, and the primary cause of tooth loss in adults. The functional and esthetic problems associated with these diseases compromise quality of life, and their treatment imposes large financial burdens on national health systems and private patients. Up-to-date knowledge of periodontal pathogenesis is therefore essential for the contemporary clinician. This book, written by experts from Europe and the Americas, delivers such knowledge in an accessible, clinician-friendly way.


Oral Microbiome Oral biofilms Periodontal inflammation Periodontal pathology Periodontium

Editors and affiliations

  • Nagihan Bostanci
    • 1
  • Georgios N. Belibasakis
    • 2
  1. 1.Department of Dental MedicineKarolinska Institute Department of Dental MedicineHuddingeSweden
  2. 2.Department of Dental MedicineKarolinska Institute Department of Dental MedicineHuddingeSweden

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG 2018
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-53735-1
  • Online ISBN 978-3-319-53737-5
  • Buy this book on publisher's site
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