© 2017

Mechanisms of Molecular Carcinogenesis – Volume 1

  • Johannes Haybaeck
  • Offers a broad and concise understanding on various tumor entities

  • Volume 1 discusses the role of stem cells in carcinogenesis

  • Provides insight into signaling pathways and tumor metabolism


Table of contents

  1. Front Matter
    Pages i-viii
  2. Giridhar Mudduluru, Katharina Ilm, Mathias Dahlmann, Ulrike Stein
    Pages 11-38
  3. Giridhar Mudduluru
    Pages 39-60
  4. Sonja M. Kessler, Alexandra K. Kiemer
    Pages 61-75
  5. Rita Seeböck, Nicole Golob-Schwarzl, Stefanie Krassnig
    Pages 77-86
  6. Peter Strasser, Serge Weis
    Pages 115-136
  7. Serge Weis, Peter Strasser
    Pages 137-150
  8. Werner Wackernagel, Lisa Tarmann, Gerald Langmann, Arun D. Singh
    Pages 151-174
  9. Rita Seeböck, Johannes Haybaeck, Oleksiy Tsybrovskyy
    Pages 175-184
  10. P. V. Tomazic
    Pages 191-197
  11. Axel Wolf
    Pages 199-204
  12. G. P. Hammer
    Pages 205-223

About this book


Divided into two volumes the work offers a so far unmatched broad and at the same time deep knowledge on molecular and cellular mechanisms of carcinogenesis and offers comprehensive insight into clinical, therapeutic and technological aspects. This 1st Volume presents tumor entities of the ocular system, the thyroid organ, the oesophagus, gliomas, non-glial brain tumors, head and neck as well as lung cancer. In addition it also discusses in-depth potential novel molecular players and the role of stem cells as well as the endocannabinoid system in carcinogenesis, it furthermore explains tumor metabolism components and signaling pathways. Each of the chapters discusses potential therapeutic strategies and novel drug targets.

The book addresses basic scientists and medical researchers interested in translational cancer research.


cancer biomarkers mechanism of carcinogenesis molecular cancer diagnostics molecular cancer profile targeted cancer therapy translational cancer research

Editors and affiliations

  • Johannes Haybaeck
    • 1
  1. 1.Department of Pathology, Medical FacultyOtto von Guericke University MagdeburgMagdeburgGermany

About the editors

Prof. Johannes Haybaeck is a professor of Pathology at the Department of Pathology, Medical Faculty of the University of Magdeburg, Germany. He is a board certified pathologist and neuropathologist who is also specialized in molecular biology. Prof. Haybaeck received his first degree in Medicine at Innsbruck University, Austria, prior to further studies at the University of Zurich, Innsbruck and Salzburg. He received his PhD degree at the Mathematical and Natural Science Faculty of the University of Zurich. Since 2010, he has led his own research group and has been a consultant for pathology and neuropathology.  In 2011, he was nominated as Vice Chair, and since 2014, he has held the title of Chairman of the Department of Neuropathology at the Medical University of Graz, Austria. He was elected as Founding Coordinator for Cancer Research, Education and Training of the Comprehensive Cancer Center (CCC) Graz for two periods. In 2016, he was nominated as Full Professor and Head of the Department of Pathology at Magdeburg University Hospital in Germany. In his capacity as a surgical pathologist and neuropathologist, he is confronted with diagnostic questions on a daily basis. Accordingly, his research focuses on the cellular and molecular mechanisms driving carcinogenesis. Together with his coworkers in Magdeburg and Graz, he is constantly engaged in the development of novel models mimicking the human situation in order to establish prognostic and predictive biomarkers and to generate novel therapies.

Bibliographic information

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