The Actin Cytoskeleton and Bacterial Infection

  • Hans Georg Mannherz

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 399)

Table of contents

  1. Front Matter
    Pages i-x
  2. Hideaki Tsuge, Toshiharu Tsurumura, Akiyuki Toda, Haruka Murata, Waraphan Toniti, Toru Yoshida
    Pages 69-86
  3. Elena Kudryashova, David B. Heisler, Dmitri S. Kudryashov
    Pages 87-112
  4. Theresia E. B. Stradal, Sonia C. P. Costa
    Pages 175-199
  5. Martin Aepfelbacher, Manuel Wolters
    Pages 201-220
  6. Pananghat Gayathri
    Pages 221-242

About this book


This volume describes the mechanisms which bacteria have created to secure their survival, proliferation and dissemination by subverting the actin cytoskeleton of host cells. Bacteria have developed a veritable arsenal of toxins, effector proteins and virulence factors that allow them to modify the properties of the intracellular actin cytoskeleton for their own purposes. Bacterial factors either modify actin directly as the main component of this part of the cytoskeleton or functionally subvert regulatory or signalling proteins terminating at the actin cytoskeleton.
In short, this volume provides an overview of the various tricks bacteria have evolved to “act on actin” in order to hijack this essential host cell component for their own needs. As such, it will be of interest to scientists from many fields, as well as clinicians whose work involves infectious diseases.


Actin cross-linking toxins Bacterial ADPPribosyltransferases Bacterial effectors Actin binding proteins Actin structure Bacterial manipulation Yersinia Bacterial actins Formins Borrelia

Editors and affiliations

  • Hans Georg Mannherz
    • 1
  1. 1.Institut für Anatomie, Abteilung für Anatomie und Molekulare EmbryologieRuhr-Universität BochumBochumGermany

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