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Fibrous Proteins: Structures and Mechanisms

  • David A.D. Parry
  • John M. Squire

Part of the Subcellular Biochemistry book series (SCBI, volume 82)

Table of contents

  1. Front Matter
    Pages i-viii
  2. John M. Squire, David A. D. Parry
    Pages 1-33
  3. Derek N. Woolfson
    Pages 35-61
  4. Marcus D. Hartmann
    Pages 63-93
  5. Andrei N. Lupas, Jens Bassler, Stanislaw Dunin-Horkawicz
    Pages 95-129
  6. Dmytro Guzenko, Anastasia A. Chernyatina, Sergei V. Strelkov
    Pages 151-170
  7. Jamal-Eddine Bouameur, Thomas M. Magin
    Pages 171-230
  8. Sarah E. Hitchcock-DeGregori, Bipasha Barua
    Pages 253-284
  9. Larissa Tskhovrebova, John Trinick
    Pages 285-318
  10. John M. Squire, Danielle M. Paul, Edward P. Morris
    Pages 319-371
  11. Olivier Delalande, Aleksander Czogalla, Jean-François Hubert, Aleksander Sikorski, Elisabeth Le Rumeur
    Pages 373-403
  12. John W. Weisel, Rustem I. Litvinov
    Pages 405-456
  13. Jordi Bella, David J. S. Hulmes
    Pages 457-490
  14. Tara D. Sutherland, Trevor D. Rapson, Mickey G. Huson, Jeffrey S. Church
    Pages 491-526
  15. Gregor Lang, Heike Herold, Thomas Scheibel
    Pages 527-573
  16. Vincent Conticello, Spencer Hughes, Charles Modlin
    Pages 575-600
  17. Barbara Brodsky, John A. M. Ramshaw
    Pages 601-629

About this book

Introduction

This book provides the readers with an up-to-date review of the design, structure and function of a representative selection of fibrous proteins in both health and disease. The importance of the α-helical coiled coil, a conformational motif based on the heptad repeat in the amino acid sequence of all α-fibrous proteins (and parts of some globular proteins) is underlined by three Chapters devoted to its design, structure, function and topology.  Specific proteins covered in the text and which depend on the coiled coil for their structure and function, include the intermediate filament proteins, tropomyosin, myosin, paramyosin, fibrin and members of the spectrin superfamily. Also described are fibrous proteins based on the β-pleated sheet and collagen conformations. Recombinant structural proteins, especially of silk and collagen, are discussed in the context of developing new biomaterials with varied applications.

Established researchers and postgraduate students in the fields of protein chemistry, biochemistry and structural biophysics will find Fibrous Proteins: Structures and Mechanisms to be an invaluable collection of topical reviews that describe the basic advances made in the field of fibrous proteins over the past decade. This book, written by recognized authorities in the field, provides a clear account of the current status of fibrous protein research and, in addition, establishes the basis for deciding the most appropriate directions for future activity, including the applications of protein engineering and the commercial exploitation of new biomaterials.

Keywords

Actin Coiled Coil α-helical coiled coil Myosin Protein Structure

Editors and affiliations

  • David A.D. Parry
    • 1
  • John M. Squire
    • 2
  1. 1.Institute of Fundamental Sciences and Riddet InstituteMassey UniversityPalmerston NorthNew Zealand
  2. 2.Muscle Contraction Group, School of Physiology, Pharmacology and NeuroscienceUniversity of BristolBristolUnited Kingdom

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-49674-0
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-49672-6
  • Online ISBN 978-3-319-49674-0
  • Series Print ISSN 0306-0225
  • Buy this book on publisher's site
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