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© 2017

Lipidomics of Stem Cells

  • Alice Pébay
  • Raymond C.B. Wong

Benefits

  • One of the few books to look at lipids and their role in stem cell biology

  • Authors are field leaders providing international perspective and expertise

  • Cohesively structured to most effectively deliver the content

Book

Part of the Stem Cell Biology and Regenerative Medicine book series (STEMCELL)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Whitney S. McDonald, Jerold Chun
    Pages 65-85
  3. Laura K. Hamilton, Karl J. L. Fernandes
    Pages 87-115
  4. Alline C. Campos, Juan Paraíso-Luna, Manoela V. Fogaça, Francisco S. Guimarães, Ismael Galve-Roperh
    Pages 117-136
  5. Alexander C. Lewis, Jason A. Powell, Stuart M. Pitson
    Pages 151-170
  6. Back Matter
    Pages 207-212

About this book

Introduction

This book combines the current knowledge on the role of lipids in stem cell pluripotency and differentiation. It showcases various approaches to the study of lipids and focuses on various types of stem cells and specific lipids driving maintenance or differentiation. The volume includes chapters reviewing roles of specific lipids in pluripotency, neurogenesis and exocytosis as well as in cancer stem cells. Examples of different classes of lipids—such as sphingolipids, lysophospholipids, cannabinoids and neutral lipids—are described and illustrate the vast biological effects of this class of molecules. The international contributors are all recognized experts in their respective fields.

Covering the various aspects of the topic, Lipidomics of Stem Cells provides an up-to-date snapshot—unique among the literature—of where the lipid world is in terms of understanding the roles of lipids in stem cell biology. It provides an essential reference for stem cell biologists, lipid biologists, development biologists, students, academics and clinicians in related areas.

Keywords

homeostasis metabolome ceramide s1p signalling lysolipids

Editors and affiliations

  • Alice Pébay
    • 1
  • Raymond C.B. Wong
    • 2
  1. 1.The University of Melbourne & Centre for Eye Research AustraliaMelbourneAustralia
  2. 2.The University of Melbourne & Centre for Eye Research AustraliaMelbourneAustralia

About the editors

Associate Professor Alice Pébay, Ph.D., is a Principal Research Fellow at the University of Melbourne and the principal investigator of the Neuroregeneration Unit at the Centre for Eye Research Australia. She holds a Ph.D. in neuroscience and has extensive expertise in cell biology, having published more than 50 peer reviewed articles and chapters in the field of stem cell biology and lysophospholipid biology. Dr Pébay's current research focuses on the mechanisms that enable human pluripotent stem cells to maintain their pluripotency and allow them differentiate towards specific retinal lineages. Dr Pébay also has comprehensive experience in neurotrauma research and a strong interest in the cellular mechanisms involved in the genetic disease, Friedreich Ataxia.

Dr. Raymond CB Wong, Ph.D., is a Senior Research Fellow at the University of Melbourne and the principal investigator of the Cellular Reprogramming Unit at the Centre for Eye Research Australia. He is a stem cell biologist specialising in human pluripotent stem cells and reprogramming. He completed his Ph.D. in stem cell biology (Monash University) and overseas postdoctoral training in University of California Irvine and subsequently National Institutes of Health. His previous research in the past 13 years has led to improvement in methods of growing and generating human pluripotent stem cells.  Dr. Wong's current research focuses on developing methods to turn human pluripotent stem cells into retinal cells, as well as utilizing human stem cells to model and study pathological progression of various retinal diseases to improve treatment options.

Bibliographic information

  • Book Title Lipidomics of Stem Cells
  • Editors Alice Pébay
    Raymond C.B. Wong
  • Series Title Stem Cell Biology and Regenerative Medicine
  • Series Abbreviated Title Stem Cell Biology,Regenerative Med.
  • DOI https://doi.org/10.1007/978-3-319-49343-5
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Humana Press, Cham
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-3-319-49342-8
  • Softcover ISBN 978-3-319-84139-7
  • eBook ISBN 978-3-319-49343-5
  • Series ISSN 2196-8985
  • Series E-ISSN 2196-8993
  • Edition Number 1
  • Number of Pages XIII, 212
  • Number of Illustrations 2 b/w illustrations, 22 illustrations in colour
  • Topics Stem Cells
    Lipidology
    Cell Physiology
    Membrane Biology
  • Buy this book on publisher's site
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