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© 2017

Obesity and Lipotoxicity

  • Ayse Basak Engin
  • Atilla Engin

Benefits

  • A comprehensive overview of obesity and lipotoxicity

  • Discusses the mechanisms of obesity and possibilities for the development of new treatment strategies

  • Overview of the biochemical pathways leading to obesity-related metabolic disorders

Book

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 960)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Atilla Engin
    Pages 53-80
  3. Loukia Vassilopoulou, Christos Psycharakis, Demetrios Petrakis, John Tsiaoussis, Aristides M. Tsatsakis
    Pages 81-110
  4. Atilla Engin
    Pages 111-134
  5. Atilla Engin
    Pages 135-160
  6. Stefania Carobbio, Vanessa Pellegrinelli, Antonio Vidal-Puig
    Pages 161-196
  7. Ayse Basak Engin
    Pages 197-220
  8. Evren Doruk Engin
    Pages 247-260
  9. Erkan Yilmaz
    Pages 261-276
  10. Dilek Yazıcı, Havva Sezer
    Pages 277-304
  11. Ayse Basak Engin
    Pages 327-343
  12. Atilla Engin
    Pages 345-379
  13. Harald Mangge, Christian Ciardi, Kathrin Becker, Barbara Strasser, Dietmar Fuchs, Johanna M. Gostner
    Pages 399-413
  14. Atilla Engin
    Pages 415-441
  15. Atilla Engin
    Pages 443-467

About this book

Introduction

Due to the resultant health consequences and considerable increase in prevalence, obesity has become a major worldwide health problem. “Obesity and Lipotoxicity” is a comprehensive review of the recent researches to provide a better understanding of the lipotoxicity-related mechanisms of obesity and the potential for the development of new treatment strategies. This book overviews the biochemical pathways leading to obesity-related metabolic disorders that occur subsequent to lipotoxicity. Chapters examine the deleterious effects of nutrient excess at molecular level including the cellular and molecular aspects of breast cancer, resistance to leptin, insulin, adiponectin, and interconnection between the circadian clock and metabolic pathways during high-fat feeding. “Lipotoxicity and Obesity” will be a useful resource for clinicians and basic science researchers, such as biochemists, toxicologists, immunologists, nutritionists, adult and pediatric endocrinologists, cardiologists, as well as students who are thought in this field.

Keywords

Adipose Tissue Hypoxia Lipolysis Lipotoxicity Obesity Protein Kinases

Editors and affiliations

  • Ayse Basak Engin
    • 1
  • Atilla Engin
    • 2
  1. 1.Faculty of Pharmacy, Department of ToxicologyGazi UniversityHipodromTurkey
  2. 2.Faculty of Medicine, Department of General SurgeryGazi UniversityBesevlerTurkey

Bibliographic information

Industry Sectors
Pharma
Chemical Manufacturing
Health & Hospitals
Biotechnology
Consumer Packaged Goods

Reviews

“The aim is to discuss the many critical and complex topics that trigger obesity with the hope that the book will encourage and further the research of scientists and practitioners who are interested in obesity. … This book is intended as a useful resource for clinicians and basic science researchers such as biochemists, toxicologists, immunologists, nutritionists, adult and pediatric endocrinologists, and cardiologists, as well as students who are interested in this field.” (L. Anne Gilmore, Doody's Book Reviews, September, 2017)