© 2017

Cancer Biomarkers in Body Fluids

Biomarkers in Circulation


Table of contents

  1. Front Matter
    Pages i-xix
  2. Gabriel D. Dakubo
    Pages 1-39
  3. Gabriel D. Dakubo
    Pages 41-69
  4. Gabriel D. Dakubo
    Pages 71-108
  5. Gabriel D. Dakubo
    Pages 109-145
  6. Gabriel D. Dakubo
    Pages 147-178
  7. Gabriel D. Dakubo
    Pages 179-212
  8. Gabriel D. Dakubo
    Pages 213-246
  9. Gabriel D. Dakubo
    Pages 247-271
  10. Gabriel D. Dakubo
    Pages 273-302
  11. Gabriel D. Dakubo
    Pages 303-324
  12. Gabriel D. Dakubo
    Pages 325-338
  13. Gabriel D. Dakubo
    Pages 339-369
  14. Gabriel D. Dakubo
    Pages 371-398
  15. Gabriel D. Dakubo
    Pages 399-416
  16. Gabriel D. Dakubo
    Pages 417-433
  17. Gabriel D. Dakubo
    Pages 435-456
  18. Gabriel D. Dakubo
    Pages 457-480
  19. Gabriel D. Dakubo
    Pages 481-497
  20. Back Matter
    Pages 499-509

About this book


This book examines in depth the evidence, clinical applications and potential cancer signatures in the circulation and discusses alterations in circulating cell-free nucleic acids, and circulating tumor DNA, as well as the epigenome, genome, transcriptome (coding and noncoding), proteome (both traditional serum proteins and proteomic profiles) and metabolome. Further, it highlights the clinical applications of circulating tumor cells for each cancer type and addresses the emerging importance of extracellular vesicular contents, including miRNA, oncogenes and drug resistant factors. As such, it offers a valuable reference guide for cancer researchers, oncologists, clinicians, surgeons, medical students, oncology nurses, diagnostic laboratories, and the pharmaceutical industry.


Body fluid biomarkers Cancer management Noninvasive diagnosis Protein targets Tissue-specific body fluids

Authors and affiliations

  1. 1.Medical Sciences Division Northern Ontario School of Medicine West CampusLakehead UniversityThunder BayCanada

About the authors

Dr. Gabriel D. Dakubo is an Assistant Professor of Molecular Medicine and Human Anatomy in the Division of Medical Sciences at the Northern Ontario School of Medicine. He received his BSc and MBChB degrees from the University of Ghana, followed by the pursuance of a Postdoctoral research fellowship in Molecular Medicine at the Ottawa Hospital Research Institute, Canada. Dr. Dakubo’s passion is in noninvasive deployment of biomarkers for cancer management. While an expert in mitochondrial genetic alterations in cancer, he also has a keen interest in the inter-genomic communications that occur in the cancer cell, as well as the Slaughter’s concept of field cancerization. Dr. Dakubo is well published, and is a reviewer of a number of esteemed journals, including Clinical Cancer Research.

Bibliographic information

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