Immunopathology in Toxicology and Drug Development

Volume 1, Immunobiology, Investigative Techniques, and Special Studies

  • George A.┬áParker

Part of the Molecular and Integrative Toxicology book series (MOLECUL)

Table of contents

  1. Front Matter
    Pages i-xxii
  2. George A. Parker, Tracey L. Papenfuss
    Pages 1-93
  3. George A. Parker
    Pages 95-201
  4. Michael C. Milone
    Pages 203-243
  5. George A. Parker
    Pages 245-294
  6. George A. Parker
    Pages 295-342
  7. George A. Parker, Paul W. Snyder
    Pages 371-442
  8. Susan A. Elmore
    Pages 443-456
  9. Josely F. Figueiredo, Kirstin F. Barnhart, Niraj Tripathi
    Pages 457-488
  10. Danielle L. Brown, Cynthia L. Swanson
    Pages 563-583
  11. Bevin Zimmerman, Jason Aligo, Daniel Weinstock
    Pages 585-600
  12. Jamie C. DeWitt, Deborah E. Keil
    Pages 601-618
  13. Ton van Huygevoort
    Pages 619-637
  14. Gary R. Burleson, Stefanie C. M. Burleson, Florence G. Burleson
    Pages 639-650
  15. Back Matter
    Pages 651-670

About this book

Introduction

This book provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies. Chapters provide an overview of general immunobiology, cells of the immune system, signaling and effector molecules, and immunopathology assays. A companion volume, Immunopathology in Toxicology and Drug Development: Volume 2, Organ Systems, offers summaries of organ-specific immunobiology and immunopathology as well as common responses to xenobiotics.

These informative and strategic books were created in response to the large segment of drug development that focuses on chronic diseases, many of which involve alterations to the immune system. Therapies that target these diseases commonly involve some form of immunomodulation. As a result, the two volumes of Immunopathology in Toxicology and Drug Development are critical texts for individuals involved in diverse aspects of drug development. Readers will acquire a thorough understanding of immunopathology for detection and accurate interpretation of pathologic effects of xenobiotics on the immune system. 

Keywords

drug development histogenesis immunomodulation immunopathology xenobiotic exposure

Editors and affiliations

  • George A.┬áParker
    • 1
  1. 1.Charles River Laboratories, Inc. HillsboroughUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-47377-2
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Humana Press, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-47375-8
  • Online ISBN 978-3-319-47377-2
  • Series Print ISSN 2168-4219
  • Series Online ISSN 2168-4235
  • About this book
Industry Sectors
Biotechnology
Consumer Packaged Goods
Pharma