© 2016


Biology, Molecular Biology, Epidemiology, and Vaccine Development

  • Sunil Thomas

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Rickettsiales: Importance and Taxonomy

    1. Front Matter
      Pages 1-1
    2. Sunil Thomas, Walker Alexander, John Gilligan, Yasuko Rikihisa
      Pages 3-21
    3. Marina E. Eremeeva
      Pages 23-57
    4. Michele Castelli, Davide Sassera, Giulio Petroni
      Pages 59-91
  3. Rickettsiales: Diagnosis and Management of Diseases

    1. Front Matter
      Pages 93-93
    2. Lucas S. Blanton
      Pages 95-107
    3. Manju Rahi, M. D. Gupte, Anurag Bhargava, George M. Varghese, Rashmi Arora
      Pages 125-133
  4. Anaplasma

    1. Front Matter
      Pages 135-135
    2. Erik Georg Granquist
      Pages 137-154
  5. Ehrlichia

    1. Front Matter
      Pages 155-155
    2. Sunil Thomas
      Pages 157-176
    3. Sunil Thomas
      Pages 177-196
    4. Stephen K. Chapes, M. Teresa Ortega, Chuanmin Cheng, Roman R. Ganta
      Pages 197-214
    5. Isabel Marcelino, Philippe Holzmuller, Frédéric Stachurski, Valérie Rodrigues, Nathalie Vachiéry
      Pages 241-280
  6. Midichloria

    1. Front Matter
      Pages 281-281

About this book


Insect-transmitted rickettsiales diseases are significant sources of morbidity and mortality all over the world. Their incidence has been increasing in recent years in large part due to climate change and the movement of animals carrying the insect vectors. Currently there are no effective vaccines against diseases caused by members of the order Rickettsiales. Rickettsiales diseases are often misdiagnosed; this book is intended to serve as a tool for their understanding and diagnosis.

Rickettsiales covers the seven main genera: Anaplasma, Ehrlichia, Midichloria, Neorickettsia, Orientia, Rickettsia and Wolbachia. Discussion of each genus includes immunology and molecular biology of host-pathogen interactions, epidemiology and diagnosis, and vaccination strategies and therapies. 


Anaplasma Ehrlichia Neorickettsia Orientia Rickettsia Wolbachia

Editors and affiliations

  • Sunil Thomas
    • 1
  1. 1.Lankenau Institute for Medical ResearchWynnewoodUSA

About the editors

Sunil Thomas
Lankenau Institute for Medical Research
Wynnewood, PA

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