© 2018

Pediatric Radiation Oncology

  • Thomas E. Merchant
  • Rolf-Dieter Kortmann


  • Describes the latest methods of targeting and treating diverse childhood cancers using radiation therapy

  • Presents recent advances in radiation oncology that promise to improve survival and cure rates

  • Written by global experts in pediatric radiation oncology


Part of the Pediatric Oncology book series (PEDIATRICO)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Thomas E. Merchant, Rolf-Dieter Kortmann
    Pages 1-2
  3. Safia K. Ahmed, Siddhartha Laskar, Nadia N. Laack
    Pages 3-20
  4. Stephanie Terezakis, Matthew Ladra
    Pages 21-43
  5. Christopher L. Tinkle, John T. Lucas Jr.
    Pages 45-85
  6. Joseph Panoff, John Lucas, Luke Pater, Shefali Gajjar
    Pages 87-110
  7. John A. Kalapurakal
    Pages 111-130
  8. Jeffrey C. Buchsbaum, Jeannette Parkes, Thanushree Naidoo
    Pages 131-170
  9. Erin Murphy, Matthew Poppe, Rakesh Jalali
    Pages 171-202
  10. Stephanie M. Perkins, Efrat Landau, Christine Hill-Kayser
    Pages 203-220
  11. Eman Al Duhaiby, Christopher Tinkle, Paul Aridgides
    Pages 221-242
  12. Erin Murphy, Shannon MacDonald, Frank Saran
    Pages 243-256
  13. Rosangela Correa Villar, Thomas E. Merchant
    Pages 257-275
  14. Thomas E. Merchant
    Pages 277-299
  15. Natia Esiashvili, Michael A. Pulsipher
    Pages 301-311
  16. Bradford S. Hoppe, Ronica H. Nanda, Anne-Marie Charpentier
    Pages 313-341
  17. Matthew D. Hall, Daniel J. Indelicato, Ronny Rotondo, Julie A. Bradley
    Pages 363-379
  18. Maurizio Mascarin, Elisa Coassin
    Pages 381-406
  19. Ralph Ermoian, Michael Rossi, Chris Beltran, Sally Rampersad
    Pages 407-417

About this book


This book presents the most up-to-date and innovative information on the targeting and treatment of a wide range of childhood cancers by means of radiation therapy. Written by global experts in pediatric radiation oncology, it documents in detail the treatment regimens appropriate to each disease, highlighting the recent advances that promise to improve rates of survival and cure. The use of image-guided and intensity-modulated radiation therapy is clearly described, and careful attention is also devoted to the roles of proton therapy, stereotactic radiosurgery, stereotactic fractionated radiosurgery, and modulated arc radiotherapy. Separate chapters address localization and verification procedures and anesthesia; pediatric radiation oncology in the palliative care setting; and aspects that are especially relevant in low- and medium-income countries. Beyond clinical radiation oncology, relevant information is provided on radiation physics. The book concludes by examining future directions in the field.


Pediatric Brain Tumors Neuroblastoma Pediatric Sarcomas Radiation Therapy Proton Therapy Palliative Care

Editors and affiliations

  • Thomas E. Merchant
    • 1
  • Rolf-Dieter Kortmann
    • 2
  1. 1.Department of Radiation OncologySt Jude Children’s Research HospitalMemphisUSA
  2. 2.Department of Radiation OncologyUniversity of LeipzigLeipzigGermany

About the editors

Dr. Thomas E. Merchant is Chair of Radiation Oncology at St. Jude Children’s Research Hospital in Memphis, Tennessee, Baddia J. Rashid Endowed Chair in Radiation Oncology, and former chairman of the Radiation Oncology Discipline, Children’s Oncology Group (COG).

Dr. Merchant is board certified in Radiation Oncology and received his medical degree from the Chicago College of Osteopathic Medicine, Chicago, Illinois and Ph.D. in experimental pathology from the University of Utrecht, The Netherlands.

As Chair of Radiation Oncology, Dr. Merchant oversees a department that includes nearly 70 faculty and staff dedicated to pediatric radiation oncology. The focus of his practice and research includes the following diseases: medulloblastoma, ependymoma, craniopharyngioma, and low-grade glioma. His special interests include brain tumors in young children, side effects of radiation therapy, re-irradiation, and proton therapy. He led the development of the St. Jude Red Frog Events Proton Therapy Center. The world’s first proton therapy center dedicated solely to the treatment of pediatric cancer patients.

Dr. Rolf-Dieter Kortmann is a Professor in Medicine and Head of Department of Radiation Therapy, University of Leipzig, Germany.

Dr. Kortmann was trained in radiology and radiooncology at the Department of Radiology and the Department of Radiooncology in Stuttgart, Essen and Tuebingen, Germany. The scientific expertise comprises quality control in radiation oncology with special emphasis on geometric precision of different radiotherapy technologies including craniospinal irradiation.

After qualification for radiation oncology in 1992, scientific research focused mainly on childhood brain tumours finally leading to the establishment of the German Study and Reference Centre for Paediatric Radiation Oncology in Childhood Brain Tumours. With the introduction of prospective brain tumour trials in Germany in the early 90s

prospective quality control programmes for radiotherapy were introduced on a nationwide level.

The activities also included prospective trials of SIOP (International Society for Paediatric Oncology) for medulloblastoma and intracranial germ cell tumours.

Since 2004 educational programmes have been created for the now independent countries of the former Soviet Union in collaboration with the International Atomic Energy Agency (IAEA) and the European Society of Therapeutic Radiation Oncology (ESTRO). Currently, ESTRO-PROS Teaching Courses are organized addressing radiation oncologists worldwide.

Special Interest: Paediatric Radiooncology, CNS Tumours, Quality Assurance

Bibliographic information

  • Book Title Pediatric Radiation Oncology
  • Editors Thomas E. Merchant
    Rolf-Dieter Kortmann
  • Series Title Pediatric Oncology
  • Series Abbreviated Title Pediatric Oncology
  • DOI
  • Copyright Information Springer International Publishing Switzerland 2018
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-3-319-43544-2
  • Softcover ISBN 978-3-030-09582-6
  • eBook ISBN 978-3-319-43545-9
  • Series ISSN 1613-5318
  • Series E-ISSN 2191-0812
  • Edition Number 1
  • Number of Pages VIII, 462
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Oncology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology


“This is an excellent complement and fortifies the libraries of both radiation and pediatric oncologists. … its updates in the rapidly changing molecular landscape of pediatric tumors, and its clear descriptions of the inexorable evolution of radiation technology, make it important reading for students, trainees, and practitioners from all disciplines who treat children with cancer.” (Bernadine Rose Donahue, Doody's Book Reviews, June, 2018)

“This book provides an excellent summary of common intracranial and extracranial pediatric malignancies treated with radiation therapy, with a focus on radiation specific treatment guidelines and clinical outcome data. The book is best suited for radiation oncologists or anyone looking for a comprehensive overview of the diagnosis and management strategies for the diseases included.” (Bree R. Eaton, Neurosurgery, Vol. 84 (3), March, 2019)