© 2018

Target Volume Delineation and Treatment Planning for Particle Therapy

A Practical Guide

  • Nancy Y. Lee
  • Jonathan E. Leeman
  • Oren Cahlon
  • Kevin Sine
  • Guoliang Jiang
  • Jiade J. Lu
  • Stefan Both
  • Provides practical information for use by the clinician and the treatment planning team on a day-to-day basis

  • Highlights essential points to which clinicians and the treatment planning team should pay attention when using particle therapy, in particular proton therapy

  • Enables clinicians to learn how to incorporate proton therapy into their clinical practice


Part of the Practical Guides in Radiation Oncology book series (PGRO)

Table of contents

  1. Natalie A. Lockney, Zhiqiang Han, Kevin Sine, Dominic Maes, Yoshiya Yamada
    Pages 317-327
  2. Anuradha Thiagarajan, Yoshiya Yamada
    Pages 329-346
  3. Curtiland Deville, Matthew Ladra, Huifang Zhai, Moe Siddiqui, Stefan Both, Haibo Lin
    Pages 347-367
  4. Bradford S. Hoppe, Stella Flampouri, Christine Hill-Kayser, John P. Plastaras
    Pages 369-380
  5. Paul B. Romesser, Nelly Ju, Chin-Cheng Chen, Kevin Sine, Oren Cahlon, Suzanne L. Wolden
    Pages 381-396

About this book


This handbook is designed to enable radiation oncologists to treat patients appropriately and confidently by means of particle therapy. The orientation and purpose are entirely practical, in that the focus is on the physics essentials of delivery and treatment planning , illustration of the clinical target volume (CTV) and associated treatment planning for each major malignancy when using particle therapy, proton therapy in particular.  Disease-specific chapters provide guidelines and concise knowledge on CTV selection and delineation and identify aspects that require the exercise of caution during treatment planning. The treatment planning techniques unique to proton therapy for each disease site are clearly described, covering beam orientation, matching/patching field techniques, robustness planning, robustness plan evaluation, etc. The published data on the use of particle therapy for a given disease site are also concisely reported. In addition to fully meeting the needs of radiation oncologists, this "know why" and “know how” guide to particle therapy will be valuable for medical physicists, dosimetrists,  and radiation therapists.


Target Delineation Proton Therapy Particle Therapy Clinical Target Volume CTV CTV Selection and Delineation Beam Orientation Matching/Patching Field Techniques Radiaton Oncology

Editors and affiliations

  • Nancy Y. Lee
    • 1
  • Jonathan E. Leeman
    • 2
  • Oren Cahlon
    • 3
  • Kevin Sine
    • 4
  • Guoliang Jiang
    • 5
  • Jiade J. Lu
    • 6
  • Stefan Both
    • 7
  1. 1.Department of Radiation OncologyMemorial Sloan-Kettering Cancer CenterNew YorkUSA
  2. 2.Department of Radiation OncologyMemorial Sloan Kettering Cancer CenterNew YorkUSA
  3. 3.Department of Radiation OncologyMemorial Sloan Kettering Cancer CenterNew YorkUSA
  4. 4.Department of Medical DosimetryProCure Proton Therapy CenterSomersetUSA
  5. 5.Department of Radiation OncologyShanghai Proton and Heavy Ion CenterShanghaiChina
  6. 6.Department of Radiation OncologyShanghai Proton and Heavy Ion CenterShanghaiChina
  7. 7.Department of Radiation OncologyUniversity Medical Center GroningenGroningenThe Netherlands

About the editors

Nancy Lee, MD:
As a board-certified radiation oncologist, Dr. Lee's expertise is using intensity-modulated radiation therapy (IMRT) to treat patients with thyroid and other head and neck cancers. Using this advanced form of 3D conformal radiotherapy, the goals are twofold — improving patients’ outcomes and decreasing the side effects of treatment.

Oren Cahlon, MD:
Dr. Cahlon is a board-certified radiation oncologist whose clinical practice is primarily focused on breast cancer. As part of a multi-disciplinary team of breast cancer experts, he works with colleagues to identify the optimal treatment approach for each patient.  At Memorial Sloan Kettering, they use the most modern radiation techniques, including prone treatment, deep inspiratory breath hold, partial breast irradiation, intensity modulated radiation therapy (IMRT) and proton therapy to deliver the most precise form of radiation.

Guoliang Jiang, MD, Shanghai Proton and Heavy Ion Center, Department of Radiation Oncology, Shanghai, China

Kevin Sine, MD, Procure Proton Therapy Center, Department of Medical Dosimetry, Somerset, NJ, USA

Jiade J. Lu, MD, Shanghai Proton and Heavy Ion Center, Department of Radiation Oncology, Shanghai, China

Jonathan Leeman, MD, Memorial Sloan-Kettering Cancer Center, Department of Radiation Oncology, New York, NY, USA

Stefan Both, PhD, Memorial Sloan-Kettering Cancer Center, Department of Medical Physics, New York, NY, USA

Bibliographic information

  • Book Title Target Volume Delineation and Treatment Planning for Particle Therapy
  • Book Subtitle A Practical Guide
  • Editors Nancy Y. Lee
    Jonathan E. Leeman
    Oren Cahlon
    Kevin Sine
    Guoliang Jiang
    Jiade J. Lu
    Stefan Both
  • Series Title Practical Guides in Radiation Oncology
  • Series Abbreviated Title Pract. Guides Radiation Oncol.
  • DOI
  • Copyright Information Springer International Publishing Switzerland 2018
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Softcover ISBN 978-3-319-42477-4
  • eBook ISBN 978-3-319-42478-1
  • Series ISSN 2522-5715
  • Series E-ISSN 2522-5723
  • Edition Number 1
  • Number of Pages VIII, 396
  • Number of Illustrations 674 b/w illustrations, 834 illustrations in colour
  • Topics Radiotherapy
Industry Sectors
Health & Hospitals
Oncology & Hematology


“This book covers treatment planning for particle therapy with a focus on protons. … This book is of high quality and provides added insights into treatment related issues in regard to particle therapy not found in most books addressing radiation therapy techniques and planning. Physicists, dosimetrists, physicians, and, to some extent, therapists interested or engaged in particle therapy will find this to be a useful addition to their library.” (Mark D. Hurwitz, Doody's Book Reviews, September, 2018)