Bone Metastases from Prostate Cancer

Biology, Diagnosis and Management

  • Francesco Bertoldo
  • Francesco Boccardo
  • Emilio Bombardieri
  • Laura Evangelista
  • Riccardo Valdagni

Table of contents

  1. Front Matter
    Pages i-x
  2. Matteo Santoni, Antonio Lopez-Beltran, Marina Scarpelli, Roberta Mazzucchelli, Rossana Berardi, Liang Cheng et al.
    Pages 25-32
  3. Massimo Gion, Chiara Trevisiol, Giulia Rainato, Aline S. C. Fabricio
    Pages 33-45
  4. Elisabetta Rossi, Rita Zamarchi
    Pages 47-59
  5. Hossein Jadvar, Laura Evangelista
    Pages 87-94
  6. Francesco Ceci, Joshua James Morigi, Lucia Zanoni, Stefano Fanti
    Pages 95-104
  7. Elisa Zanardi, Carlo Cattrini, Francesco Boccardo
    Pages 105-120
  8. Giovanni Luca Ceresoli, Maria Bonomi, Maria Grazia Sauta
    Pages 121-133
  9. Giovanni Luca Ceresoli, Maria Bonomi, Maria Grazia Sauta, Elisa Zanardi, Francesco Boccardo
    Pages 135-146
  10. Alessandro Luzzati, Gennaro Scotto, Giuseppe Perrucchini, Carmine Zoccali
    Pages 147-161
  11. Barbara Avuzzi, Riccardo Valdagni
    Pages 163-180
  12. Daniele Santini, Carla Ripamonti, Alice Zoccoli, Michele Iuliani, Marco Fioramonti, Giulia Ribelli et al.
    Pages 181-192
  13. Joe O’Sullivan, Phil Turner
    Pages 193-207
  14. Sergio Bracarda, Alketa Hamzaj, Kalliopi Andrikou
    Pages 209-221
  15. Emilio Bombardieri, Francesco Mungai, Maria Bonomi, Lucia Setti, Eugenio Borsatti, Gianluigi Ciocia et al.
    Pages 223-249
  16. Augusto Caraceni, Ernesto Zecca, Fabio Formaglio, Francesca Ricchini
    Pages 251-270
  17. Umberto Restelli, Luca Dellavedova, Davide Croce, Lorenzo Maffioli
    Pages 271-279
  18. Tiziana Magnani, Lara Bellardita, Augusto Caraceni, Filippo de Braud, Giuseppe Procopio, Roberto Salvioni et al.
    Pages 281-293

About this book


This book presents up-to-date information on one of the hottest topics in prostate cancer, namely bone metastases. The most recent developments with respect to biology, pathology, diagnosis, and treatment are described, providing readers with an excellent understanding of the mechanisms of metastasis formation, the characteristics of metastases, their aggressiveness, and prognostic factors for treatment response. The coverage includes discussion of all of the best available options (laboratory, radiology, and nuclear medicine) for achieving early diagnosis and both established and novel therapeutic approaches. Detailed information is provided on hormonal manipulations, bone-targeted agents, vaccines, taxanes, and other treatments that are enriching the therapeutic armamentarium. The editors can be considered leaders in the field, with great experience in diagnostic and clinical oncology and research, and the authors are experts in diverse specialties. This ensures a multidisciplinary approach, mirroring the current situation in which treatment in patients with bone metastases is undertaken by a team of specialists and health professionals in a variety of fields.


Bone-targeted agents Markers of prostate cancer Formation of bone metastases Nuclear medicine techniques Radiotherapy for bone metastases Bone-seeking radionuclides Circulating cells Hormonal therapy Combined hormonal therapy and chemotherapy

Editors and affiliations

  • Francesco Bertoldo
    • 1
  • Francesco Boccardo
    • 2
  • Emilio Bombardieri
    • 3
  • Laura Evangelista
    • 4
  • Riccardo Valdagni
    • 5
  1. 1.University of VeronaDirector of Metabolic Bone Diseases and Osteoncology Unit, Internal Medicine Department of MedicineVeronaItaly
  2. 2.IRCCS AOU San Martino-IST National Cancer Research InstituteDepartment of Internal Medicine and Medical specialties (DIMI), School of Medical and Pharmacological Sciences, University of Genoa, Academic Unit of Medical Oncology, Department of Oncology (DIPOE)GenoaItaly
  3. 3.Humanitas Gavazzeni ClinicClical Scientific Director Department of Nuclear MedicineBergamoItaly
  4. 4.Veneto Institute of Oncology IOV - IRCCSNuclear Medicine and Molecular imaging UnitPadovaItaly
  5. 5.Radiation Oncology 1 and Prostate Cancer Program, Fondazione IRCCS Istituto Nazionale dei TumoriDepartment of Oncology and Hemato-oncology, Università di MilanoMilanItaly

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2017
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-319-42326-5
  • Online ISBN 978-3-319-42327-2
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology