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Proteogenomics

  • Ákos Végvári

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 926)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Kelly V. Ruggles, David Fenyö
    Pages 11-19
  3. Ruggero Barbieri, Victor Guryev, Corry-Anke Brandsma, Frank Suits, Rainer Bischoff, Peter Horvatovich
    Pages 21-47
  4. Volodimir Olexiouk, Gerben Menschaert
    Pages 49-64
  5. Marc Vaudel, Harald Barsnes, Helge Ræder, Frode S. Berven
    Pages 65-75
  6. Ákos Végvári
    Pages 77-91
  7. Alba Garin-Muga, Fernando J. Corrales, Victor Segura
    Pages 93-113
  8. Christer Wingren
    Pages 163-179
  9. Back Matter
    Pages 181-184

About this book

Introduction

This book highlights key technologies and identifies areas for further development in proteogenomics. The utility and usefulness of very large Omics data sets (Next Gen Sequencing of DNA, RNA-seq, ribosome profiling, mass spectrometry- and antibody-based proteomics) is discussed and opportunities and challenges of related bioinformatics applications are outlined.

The reader will be able to appreciate the interdisciplinary nature of the continuously evolving area of proteogenomics, which has already grown beyond its original concept of verifying gene annotations by proteomics. The chapters presented in this book are arranged to offer a general overview, rather than to provide detailed descriptions of technologies. The selected applications will provide useful insight into the level of detail that can be obtained in relation to certain diseases areas, including cancer biology and personalized medicine. The readers will find that each chapter delivers a comprehensive approach to proteogenomics, each from the point of view of a specific application.

Research scientists interested in innovative processes that can offer a unique and at the same time a more complete access to technological developments and concepts that in turn can contribute to a better understand biological functions should read this book. 

Keywords

Genomics Improve Gene Annotations Post-Translational Modification Proteomics Signal Peptides

Editors and affiliations

  • Ákos Végvári
    • 1
  1. 1.Department of Pharmacology & ToxicologyUniversity of Texas Medical BranchGalvestonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-42316-6
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-42314-2
  • Online ISBN 978-3-319-42316-6
  • Series Print ISSN 0065-2598
  • Series Online ISSN 2214-8019
  • Buy this book on publisher's site
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