© 2017

Hematologic Abnormalities and Acute Lung Syndromes

  • Janet S. Lee
  • Michael P. Donahoe


  • First book of its kind to focus solely on acute lung processes stemming from primary hematologic disorders or complications of treatment

  • Provides clinical guidelines for addressing hematologic complications in the ICU

  • Chapters are organized for easy reference and emphasize primary literature


Part of the Respiratory Medicine book series (RM)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Overview

    1. Front Matter
      Pages 1-1
    2. Peng Zhang, Janet S. Lee
      Pages 3-17
    3. Prithu Sundd, Margaret F. Bennewitz
      Pages 19-45
  3. Acute Pulmonary Manifestations Arising From Primary Hematologic Disorders

    1. Front Matter
      Pages 47-47
    2. Olufolake Adetoro Adisa, Amma Owusu-Ansah, Afua Darkwah Abrahams, Samit Ghosh, Solomon Fiifi Ofori-Acquah
      Pages 49-65
    3. Shani Gunning-Carter, Gregory J. Kato, Belinda Rivera-Lebron
      Pages 89-108
    4. Andra Fee-Mulhearn, Patrick Nana-Sinkam
      Pages 131-146
    5. Guang-Shing Cheng, David K. Madtes
      Pages 147-171
  4. Transfusion-Related Complications

    1. Front Matter
      Pages 173-173
    2. Stefanie Forest, Francesca Rapido, Eldad A. Hod
      Pages 175-191
    3. Mario V. Fusaro, Giora Netzer
      Pages 229-239
  5. Back Matter
    Pages 261-265

About this book


This book provides a unique frame work for examining acute lung syndromes that arise from hematologic disorders or is defined by a hematologic abnormality as a key feature.  Acute lung processes arising from hematologic disorders can present as life-threatening conditions, and as such, the pulmonary physician or critical care physician are often directly involved in care or called upon to provide expertise. Chapters are organized into three sections, each with an emphasis on pathogenesis and current understanding of mechanisms. The text begins with the central theme of the lungs as the direct interface between the external environment and blood, description of individual components of the hematopoietic system, their function and relevance to the lungs. The second section outlines both benign and malignant primary hematologic disorders that can lead to acute pulmonary manifestations. The final section focuses on acute lung syndromes stemming from complications of transfusion and treatment. Chapters are presented in an easy-to-access format, providing information on diagnosis, management, and outcomes. This is a valuable resource for pulmonary fellows in training, pulmonologists, critical care physicians, and physicians involved in caring for patients in the ICU.


acute chest syndrome acute lung syndromes diffuse alveolar hemorrhage hematologic abnormalities thrombophilia transfusion-related acute lung injury

Editors and affiliations

  • Janet S. Lee
    • 1
  • Michael P. Donahoe
    • 2
  1. 1.Division of Pulmonary, Allergy, and Critical Care Medicine Department of MedicineUniversity of Pittsburgh School of MedicinePittsburghUSA
  2. 2.Division of Pulmonary, Allergy, and Critical Care Medicine Department of MedicineUniversity of Pittsburgh School of MedicinePittsburghUSA

About the editors

Janet S. Lee Associate Professor of Medicine Division of Pulmonary, Allergy, Critical Care Medicine University of Pittsburgh Pittsburgh, PA 15213

Bibliographic information

  • Book Title Hematologic Abnormalities and Acute Lung Syndromes
  • Editors Janet S. Lee
    Michael P. Donahoe
  • Series Title Respiratory Medicine
  • Series Abbreviated Title Respiratory Medicine
  • DOI
  • Copyright Information Springer International Publishing Switzerland 2017
  • Publisher Name Humana Press, Cham
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-3-319-41910-7
  • Softcover ISBN 978-3-319-82462-8
  • eBook ISBN 978-3-319-41912-1
  • Series ISSN 2197-7372
  • Series E-ISSN 2197-7380
  • Edition Number 1
  • Number of Pages XI, 265
  • Number of Illustrations 11 b/w illustrations, 19 illustrations in colour
  • Topics Pneumology/Respiratory System
    Intensive / Critical Care Medicine
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology


“This monograph is devoted to the presentation of pulmonary manifestations of hematologic disorders. … Senior critical care trainees, pulmonologists, intensivists, and hematologists are an appropriate audience. … This book brings a unique and effective combination of pulmonary and hematology expertise to bear on pulmonary manifestations of blood disorders. Chapters are brief, detailed and readable. Medical intensivists, in particular, will find this work helpful.” (David J. Dries, Doody's Book Reviews, April, 2017)