© 2016

Epigenetics in Cardiac Disease

  • Johannes Backs
  • Timothy A. McKinsey
  • The first book dedicated to epigenetic regulation in cardiac diseases

  • Provides insight into the complexity of histon and DNA modifications that contribute to cardiac development and the pathogenesis of cardiac diseases

  • Offers a broad overview on the topic and discusses the latest advances in the field


Part of the Cardiac and Vascular Biology book series (Abbreviated title: Card. vasc. biol., volume 1)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Genevieve P. Delcuve, Dilshad H. Khan, Vichithra R. B. Liyanage, Sanzida Jahan, Mojgan Rastegar, Lorrie A. Kirshenbaum et al.
    Pages 1-35
  3. Mei Xin, Kunhua Song
    Pages 53-73
  4. Justus Stenzig, Roger S-Y Foo
    Pages 75-102
  5. Pei Han, Jin Yang, Ching Shang, Ching-Pin Chang
    Pages 103-124
  6. Nanette H. Bishopric
    Pages 147-190
  7. Mariya Kronlage, Hugo A. Katus, Johannes Backs
    Pages 191-208
  8. Weston W. Blakeslee, Philip D. Tatman, Timothy A. McKinsey
    Pages 209-229
  9. Sadhana Samant, Mahesh P. Gupta
    Pages 263-282
  10. Priti Anand, Amir Munir, Saptarsi M. Haldar
    Pages 283-296
  11. Constantin Kühl, Norbert Frey
    Pages 297-316
  12. Johannes Backs, Timothy A. McKinsey
    Pages C1-C1

About this book


This book describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone modifications) and of chromatin regulators in the context of cardiac diseases. The book provides readers with an overview of our current understanding of epigenetic regulation in the heart, and will stimulate further research in this exciting field. Edited and written by internationally respected experts, it addresses the needs of professors, students and researchers working in the fields of cardiac biology and epigenetics.


Cardiac development Cardiopulmonary Remodeling Chromatin remodeling DNA methylation Heart failure Histone Deacetylases

Editors and affiliations

  • Johannes Backs
    • 1
  • Timothy A. McKinsey
    • 2
  1. 1.Department of Molecular, Cardiology and EpigeneticsUniversity of HeidelbergHeidelbergGermany
  2. 2.Department of Medicine, Division of CardiologyUniversity of Colorado DenverAuroraUSA

About the editors

Prof. Johannes Backs, MD Research Unit Cardiac Epigenetics University of Heidelberg Im Neuenheimer Feld 410 69221 Heidelberg Germany

Prof. Timothy A. McKinsey, PhD Department of Medicine/Division of Cardiology University of Colorado Denver 12700 E 19th Avenue Aurora CO 80045 USA

Bibliographic information

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