© 2016

Glial Cells in Health and Disease of the CNS

  • Rommy von Bernhardi
  • Covers each of the three major types of glial cells in the CNS

  • Timely overview of a growing topic

  • Gathers contributions from leading researchers in the field


Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 949)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Rommy von Bernhardi, Jaime Eugenín-von Bernhardi, Betsi Flores, Jaime Eugenín León
    Pages 1-24
  3. Glial Cell Function in the Healthy Nervous System

    1. Front Matter
      Pages 25-25
    2. Jaime Eugenín-von Bernhardi, Leda Dimou
      Pages 27-45
    3. Fernando Peña-Ortega, Ana Julia Rivera-Angulo, Jonathan Julio Lorea-Hernández
      Pages 47-66
    4. Rommy von Bernhardi, Florencia Heredia, Nicole Salgado, Paola Muñoz
      Pages 67-92
    5. Jaime Eugenín León, María José Olivares, Sebastián Beltrán-Castillo
      Pages 109-145
    6. Bernardo Castellano, Mar Bosch-Queralt, Beatriz Almolda, Nàdia Villacampa, Berta González
      Pages 147-165
  4. Glial Cell Dysfunction and Pathological Implications

    1. Front Matter
      Pages 203-203
    2. Francisca Cornejo, Rommy von Bernhardi
      Pages 205-226
    3. Silvia Olivera-Bravo, Eugenia Isasi, Anabel Fernández, Gabriela Casanova, Juan Carlos Rosillo, Luigi Barbeito
      Pages 227-243
    4. Anna Carolina Carvalho da Fonseca, Rackele Amaral, Celina Garcia, Luiz Henrique Geraldo, Diana Matias, Flavia Regina Souza Lima
      Pages 245-261
    5. Verónica Murta, Carina Ferrari
      Pages 263-285
    6. Adrián Sandoval-Hernández, María José Contreras, Jenny Jaramillo, Gonzalo Arboleda
      Pages 287-310
    7. Penha Cristina Barradas, Tiago Savignon, Alex C. Manhães, Frank Tenório, Alan P. da Costa, Marta C. Cunha-Rodrigues et al.
      Pages 333-345
  5. Back Matter
    Pages 347-348

About this book


A timely overview covering the three major types of glial cells in the central nervous system - astrocytes, microglia, and oligodendrocytes. New findings on glia biology are overturning a century of conventional thinking about how the brain operates and are expanding our knowledge about information processing in the brain. The book will present recent research findings on the role of glial cells in both healthy function and disease. It will comprehensively cover a broad spectrum of topics while remaining compact in size.


aging cytotoxicity disease mechanisms glial cells neurodegenerative disease neuroinflammation

Editors and affiliations

  • Rommy von Bernhardi
    • 1
  1. 1.Faculty of Medicine Professor of NeurologyPontificia Universidad Católica de ChileSantiagoChile

About the editors

Rommy von Bernhardi is professor of Neurology at the School of Medicine, Pontificia Universidad Católica de Chile (Santiago, Chile) and head of the Neuroscience lab. She obtained her Ph.D. in Neuroscience at the Universität Basel (Basel, Switzerland). Her research areas of interest concern: the biological mechanisms of clinical diseases of the CNS--particularly Alzheimer's disease and neurodegenerative pathology; as well as the functional and disease-related role of glial cells in the inflammation of the nervous system. She is coauthor and coeditor of over 80 scientific publications. Dr. Von Bernhardi is also a member of several distinguished societies such as the Society for Neuroscience and the International Brain Research Organization (IBRO); she was president of the Sociedad Chilena Neurociencia and is currently head of FALAN (Federación Latinoamericana y del Caribe de Neurociencia). 

Bibliographic information

  • Book Title Glial Cells in Health and Disease of the CNS
  • Editors Rommy von Bernhardi
  • Series Title Advances in Experimental Medicine and Biology
  • Series Abbreviated Title Adv Exp Med Biol
  • DOI
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-3-319-40762-3
  • Softcover ISBN 978-3-319-82176-4
  • eBook ISBN 978-3-319-40764-7
  • Series ISSN 0065-2598
  • Series E-ISSN 2214-8019
  • Edition Number 1
  • Number of Pages XI, 348
  • Number of Illustrations 11 b/w illustrations, 35 illustrations in colour
  • Topics Neurosciences
  • Buy this book on publisher's site
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