Obesity, Type 2 Diabetes and the Adipose Organ

A Pictorial Atlas from Research to Clinical Applications

  • Saverio Cinti

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Saverio Cinti
    Pages 1-11
  3. Saverio Cinti
    Pages 13-79
  4. Saverio Cinti
    Pages 81-105
  5. Saverio Cinti
    Pages 107-155
  6. Saverio Cinti
    Pages 157-179
  7. Saverio Cinti
    Pages 181-203
  8. Saverio Cinti
    Pages 205-251
  9. Saverio Cinti
    Pages 253-263
  10. Saverio Cinti
    Pages 265-305
  11. Saverio Cinti
    Pages 307-335
  12. Saverio Cinti
    Pages 337-383
  13. Saverio Cinti
    Pages 385-423
  14. Saverio Cinti
    Pages 425-455

About this book


This richly illustrated book provides a detailed description of the gross anatomy, light microscopy, immunohistochemistry, and electron microscopy of the adipose organ, which comprises subcutaneous and visceral fat depots. Findings in mice of differing genetic backgrounds (obesity prone and resistant) and maintained in standard and various physiologic and pathologic conditions are presented. The latter conditions include chronic cold exposure, warm exposure, fasting, pregnancy–lactation, and obesity. Features of the fetal adipose organ are described in a separate chapter, and results from transgenic mice are also presented when relevant. The human adipose organ is addressed in several chapters that include magnetic resonance and fetal findings. Most of the results regarding the adipose organ anatomy in different physiologic conditions are new, and the story of pink adipocytes (white-to-pink transdifferentiation) is quite innovative. The concept of using browning of the adipose organ as a therapeutic tool for obesity must take into consideration the anatomic and morphologic aspects described here, and the study of pink adipocytes could lead to a better comprehension of breast cancer tumor biology. This book will be of interest to all scientists who deal with obesity and related disorders.


Brown adipocytes Brown adipose tissue Cold acclimation Pink adipocytes Transdifferentiation Warm acclimation White adipocytes White adipose tissue

Authors and affiliations

  • Saverio Cinti
    • 1
  1. 1.Professor of Anatomy, Director, Center of ObesityUniversity of Ancona (Politecnica delle Marche)AnconaItaly

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2018
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-319-40520-9
  • Online ISBN 978-3-319-40522-3
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology