Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy

New Perspectives and Opportunities

  • Christopher D. Gregory

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 930)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Christopher P. Dillon, Douglas R. Green
    Pages 1-23
  3. Christopher D. Gregory, Catriona A. Ford, Jorine J. L. P. Voss
    Pages 51-88
  4. Peter Vandenabeele, Katrien Vandecasteele, Claus Bachert, Olga Krysko, Dmitri V. Krysko
    Pages 133-149
  5. Benjamin Frey, Anja Derer, Heike Scheithauer, Roland Wunderlich, Rainer Fietkau, Udo S. Gaipl
    Pages 151-172
  6. Mike-Andrew Westhoff, Nicolas Marschall, Klaus-Michael Debatin
    Pages 173-204
  7. Andreas Weigert, Javier Mora, Divya Sekar, Shahzad Syed, Bernhard Brüne
    Pages 205-239
  8. Back Matter
    Pages 241-247

About this book


This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic apoptotic cell death and anti-cancer immunity and cancer cell death-inducing radiotherapy. This book places the onco-biology of apoptosis in clear and objective perspective through an expertly synthesized series of reviews.

Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy is a deft and thorough exploration of cutting-edge research in apoptosis and anti-cancer mechanisms from basic biology to oncology. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike.


cell death inflammation macrophages oncogenes phagocytes tumors

Editors and affiliations

  • Christopher D. Gregory
    • 1
  1. 1.MRC Centre for Inflammation ResearchUniversity of Edinburgh Queen’s Medical Research InstituteEdinburghUnited Kingdom

Bibliographic information

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