© 2017

Biomarkers of the Tumor Microenvironment

Basic Studies and Practical Applications

  • Lars A. Akslen
  • Randolph S. Watnick

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Basic Mechanisms and Biomarkers

    1. Front Matter
      Pages 1-1
    2. Candice Alexandra Grzelak, Andrea Rachel Lim, Cyrus Michael Ghajar
      Pages 25-53
    3. Cédric Zeltz, Roya Navab, Marion Kusche-Gullberg, Ming-Sound Tsao, Donald Gullberg
      Pages 77-112
    4. Megan L. Sulciner, Molly M. Gilligan, Bruce R. Zetter, Dipak Panigrahy
      Pages 167-193
    5. Stalin Chellappa, Einar M. Aandahl, Kjetil Taskén
      Pages 195-220
    6. Rolf A. Brekken, Katarzyna Wnuk-Lipinska
      Pages 221-239
    7. Alexandre Corthay, Guttorm Haraldsen
      Pages 241-257
    8. Gert G. G. M. Van den Eynden, Roberto Salgado, Karen Willard-Gallo
      Pages 259-280
    9. Kelly E. Johnson, Sandra S. McAllister, Joseph E. Italiano Jr., Elisabeth M. Battinelli
      Pages 281-302
    10. Tina El Rayes, Dingcheng Gao, Nasser K. Altorki, Thomas R. Cox, Janine T. Erler, Vivek Mittal
      Pages 303-328
    11. Xiaoran Li, Diane R. Bielenberg
      Pages 329-349
    12. Kjersti T. Davidsen, Gry S. Haaland, Maria K. Lie, James B. Lorens, Agnete S. T. Engelsen
      Pages 351-376
  3. Organ Related Biomarker Studies

    1. Front Matter
      Pages 377-377
    2. Eugene Kim, Morteza Esmaeili, Siver A. Moestue, Tone F. Bathen
      Pages 409-431

About this book


This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Practical applications, in terms of how biomarkers are increasingly included in therapy protocols, will also be discussed. 

Biomarkers of the Tumour Microenvironment: Basic Studies and Practical Applications is aimed at research pathologists in the cancer field, and also cancer researchers from other backgrounds, especially those using morphology techniques and models focusing on cross-talk between different cell types in tumors.


biomarker morphology tumor microenvironment tumor-vascular interaction cancer microenvironment

Editors and affiliations

  • Lars A. Akslen
    • 1
  • Randolph S. Watnick
    • 2
  1. 1.Centre for Cancer Biomarkers CCBIO, Department of Clinical MedicineUniversity of BergenBergenNorway
  2. 2.Vascular Biology Program, Department of SurgeryBoston Children’s Hospital, Harvard Medical SchoolBostonUSA

About the editors

Lars A. Akslen, M.D., Ph.D., Centre for Cancer Biomarkers, Department of Clinical Medicine, The Gade Laboratory for Pathology University of Bergen, NORWAY 
Randolph S. Watnick, Ph.D., Assistant Professor, Department of Surgery, Harvard Medical School, Vascular Biology Program, Boston Children's Hospital Boston, USA

Bibliographic information

  • Book Title Biomarkers of the Tumor Microenvironment
  • Book Subtitle Basic Studies and Practical Applications
  • Editors Lars A. Akslen
    Randolph S. Watnick
  • DOI
  • Copyright Information Springer International Publishing Switzerland 2017
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-3-319-39145-8
  • Softcover ISBN 978-3-319-81829-0
  • eBook ISBN 978-3-319-39147-2
  • Edition Number 1
  • Number of Pages XVII, 534
  • Number of Illustrations 1 b/w illustrations, 51 illustrations in colour
  • Topics Pathology
    Cancer Research
  • Buy this book on publisher's site
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