Hepatocellular Carcinoma

Diagnosis and Treatment

  • Brian I. Carr

Part of the Current Clinical Oncology book series (CCO)

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Causes, Biological and Molecular Bases of HCC

    1. Front Matter
      Pages 1-1
    2. Donna L. White, Fasiha Kanwal, Li Jiao, Hashem B. El-Serag
      Pages 3-24
    3. Hani Alotaibi, Nese Atabey, Kasım Diril, Esra Erdal, Mehmet Ozturk
      Pages 43-63
    4. Yvonne P. Dragan
      Pages 65-92
    5. Anuradha Budhu, Xin Wei Wang
      Pages 93-112
    6. Jean-Charles Nault, Jessica Zucman-Rossi
      Pages 113-119
    7. Aldo Cavallini
      Pages 121-137
    8. Nicolas Goossens, Ismail Labgaa, Augusto Villanueva
      Pages 139-147
    9. Sven H. Loosen, Christoph Roderburg, Tom Luedde
      Pages 149-155
    10. Antonio Mazzocca, Giovanni Ferraro, Giovanni Misciagna, Brian I. Carr
      Pages 157-161
    11. Brian I. Carr
      Pages 163-166
    12. Evgeny V. Denisov, Tatiana S. Gerashchenko, Marina V. Zavyalova, Vasiliy N. Manskikh, Evgeny L. Choinzonov, Nadezhda V. Cherdyntseva et al.
      Pages 211-228
    13. Inbal Houri, Oren Shibolet
      Pages 243-259
    14. Ryota Masuzaki, Tatsuo Kanda, Haruhiko Yoshida, Naoya Kato, Masao Omata
      Pages 261-273
    15. Chadia L. Robertson, Devanand Sarkar, Arun J. Sanyal
      Pages 275-286
    16. David H. Van Thiel, Salamah Mohammad Alwahsh, Giuliano Ramadori
      Pages 287-301
  3. Diagnosis

    1. Front Matter
      Pages 303-303
    2. Michael A. Nalesnik
      Pages 305-329
    3. Cristina Della Corte, Massimo Colombo
      Pages 339-354
    4. Tae Kyoung Kim, Hyun-Jung Jang, Stephanie R. Wilson
      Pages 367-390
    5. Anuj Patel, Neil Malhotra, Christopher G. Roth, Sandeep Deshmukh, Donald G. Mitchell
      Pages 391-397
    6. Francesco Agnello, Giuseppe Brancatelli
      Pages 399-408
    7. Yukio Tokumitsu, Hiroaki Nagano
      Pages 425-442
  4. Therapies

    1. Front Matter
      Pages 443-443
    2. Tito Livraghi, Maria Franca Meloni, Anita Andreano
      Pages 445-452
    3. Antonio Facciorusso, Michele Barone
      Pages 453-466
    4. Nir Lubezky, Yaacov Goykhman, Richard Nakache, Ido Nachmany
      Pages 467-475
    5. Georg Györi, Pierre-Alain Clavien, Mickaël Lesurtel
      Pages 477-488
    6. Brian I. Carr, Srikanth Nagalla, Ravit Geva
      Pages 489-512
    7. Susan Kralian, Brian I. Carr
      Pages 513-529
    8. Andrew S. Kennedy
      Pages 531-546
    9. Jennifer L. Steel, Feridey N. Carr, Alexandra Savkova, Naadia Ahmed, Andrea DiMartini, Mary A. Dew
      Pages 547-577
    10. Brian I. Carr
      Pages 579-584
  5. Back Matter
    Pages 585-596

About this book


Hepatocellular carcinoma (HCC) used to be regarded as a rare disease. However, the increasing numbers of chronic HCC carriers in the U.S. and subsequent increased incidences of HCC seen in most large medical centers means that it is no longer an uncommon disease for gastroenterologists or oncologists to encounter and its incidence and epidemiology are changing. During this exciting time in the field of HCC basic science and clinical management, many changes are simultaneously occurring at multiple levels of our understanding and management of the disease. Suddenly, there are several new choices of therapy to offer patients. Hepatocellular Carcinoma, 3rd edition addresses this fast-changing disease and gives the reader a clearer understanding of the many mechanisms involved in carcinogenesis of the liver. This comprehensive and detailed review of how to diagnose and treat hepatocellular carcinoma is written by international leaders in the field, covering both clinical treatment choices and the basic science underlying HCC development. Updated and enhanced from the last edition in 2009, Hepatocellular Carcinoma, 3rd edition features 12 new chapters including discussion of molecular markers, molecular hepatocarcinogenesis, microenvironment, heterogeneity, the new and exciting contributions of immunotherapy, and updates on the major effective hepatitis therapies that will transform HCC indidence and perhaps also the therapy. This cutting-edge text is a vital resource and must-have for today’s hepatologists and medical and surgical oncologists. 

"This is a well written text and should be a good reference book for those who see patients with HCC.." - Practical Gastroenterology

"...a useful tool for both physicians and surgeons with a specific interest in the management of patients with HCC." - Digestive and Liver Disease


gastroenterology hepatocellucal carcinoma oncology surgical oncology hepatology

Editors and affiliations

  • Brian I. Carr
    • 1
  1. 1.Dokuz Eylul UniversityIzmir Biomedicine and Genome Center Dokuz Eylul UniversityIzmirTurkey

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-319-34212-2
  • Online ISBN 978-3-319-34214-6
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology