© 2016

Translational Neuropsychopharmacology

  • Trevor W. Robbins
  • Barbara J. Sahakian

Part of the Current Topics in Behavioral Neurosciences book series (CTBN, volume 28)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Tatiana M. Kazdoba, Prescott T. Leach, Mu Yang, Jill L. Silverman, Marjorie Solomon, Jacqueline N. Crawley
    Pages 1-52
  3. Catharine A. Winstanley, Luke Clark
    Pages 93-120
  4. Mary Falcone, Bridgin Lee, Caryn Lerman, Julie A. Blendy
    Pages 121-150
  5. Markus Heilig, Wolfgang H. Sommer, Rainer Spanagel
    Pages 151-171
  6. Marijn C. W. Kroes, Daniela Schiller, Joseph E. LeDoux, Elizabeth A. Phelps
    Pages 197-230
  7. Andre Der-Avakian, Samuel A. Barnes, Athina Markou, Diego A. Pizzagalli
    Pages 231-262
  8. E.S.J. Robinson, J.P. Roiser
    Pages 263-286
  9. Jared W. Young, Arpi Minassian, Mark A. Geyer
    Pages 287-303
  10. Cindy Lustig, Martin Sarter
    Pages 327-362
  11. Verity J. Brown, David S. Tait
    Pages 363-395
  12. M. Hvoslef-Eide, S. R. O. Nilsson, L. M. Saksida, T. J. Bussey
    Pages 423-447
  13. Jennifer H. Barnett, Andrew D. Blackwell, Barbara J. Sahakian, Trevor W. Robbins
    Pages 449-474

About this book


This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importance of intermediate staging points between these extremes that depend on suitable translation of findings from animal studies to Phase 1 or Phase 2 studies utilising experimental medicine.  


Depression models Psychiatric and neurological disorders Schizophrenia models Translational approaches to anxiety Translational models Translational neuropsychopharmacology

Editors and affiliations

  • Trevor W. Robbins
    • 1
  • Barbara J. Sahakian
    • 2
  1. 1.University of CambridgeCambridgeUK
  2. 2.University of CambridgeCambridgeUK

Bibliographic information

  • Book Title Translational Neuropsychopharmacology
  • Editors Trevor W. Robbins
    Barbara J. Sahakian
  • Series Title Current Topics in Behavioral Neurosciences
  • Series Abbreviated Title CTBN
  • DOI
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-3-319-33911-5
  • Softcover ISBN 978-3-319-81630-2
  • eBook ISBN 978-3-319-33913-9
  • Series ISSN 1866-3370
  • Series E-ISSN 1866-3389
  • Edition Number 1
  • Number of Pages XII, 498
  • Number of Illustrations 32 b/w illustrations, 92 illustrations in colour
  • Topics Neurosciences
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals


“This book examines the ‘translational gap’ between animal models of neuropsychiatric disease and human studies. … The intended audience is scientists working on problems related to neuropsychopharmacology. … This is an important addition to the literature on translational neurosciences. It is an important contribution to understanding both the current state of this field and its possible future directions.” (Eric Gausche, Doody's Book Reviews, November, 2016)