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Manipulation of Multiphase Materials for Touch-less Nanobiotechnology

A Pyrofluidic Platform

  • Sara Coppola

Part of the Springer Theses book series (Springer Theses)

Table of contents

About this book

Introduction

The thesis presents an original and smart way to manipulate liquid and polymeric materials using a “pyro-fluidic platform” which exploits the pyro-electric effect activated onto a ferroelectric crystal. It describes a great variety of functionalities of the pyro-electrohydrodynamic platform, such as droplet self-assembling and dispensing, for manipulating multiphase liquids at the micro- and nanoscale. The thesis demonstrates the feasibility of non-contact self-assembling of liquids in plane (1D) using a micro engineered crystal, improving the dispensing capability and the smart transfer of material between two different planes (2D) and controlling and fabricating three-dimensional structures (3D).

The thesis present the fabrication of highly integrated and automated ‘lab-on-a-chip’ systems based on microfluidics. The pyro-platform presented herein offers the great advantage of enabling the actuation of liquids in contact with a polar dielectric crystal through an electrode-less configuration. The simplicity and flexibility of the method for fabricating 3D polymer microstructures shows the great potential of the pyro-platform functionalities, exploitable in many fields, from optics to biosensing. In particular, this thesis reports the fabrication of optically active elements, such as nanodroplets, microlenses and microstructures, which have many potential applications in photonics.

The capability for manipulating the samples of interest in a touch-less modality is very attractive for biological and chemical assays. Besides controlling cell growth and fate, smart micro-elements could deliver optical stimuli from and to cells monitoring their growth in real time, opening interesting perspectives for the realization of optically active scaffolds made of nanoengineered functional elements, thus paving the way to fascinating Optogenesis Studies.

Keywords

Lab-on-a-chip 3D lithography Polymer micro lenses Drug delivery through microneedles Liquids self-assembly Pyro-electric effect

Authors and affiliations

  • Sara Coppola
    • 1
  1. 1.Ist. di Scienze Applicate e SistemiCNR-ISASIPozzuoliItaly

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-31059-6
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Chemistry and Materials Science
  • Print ISBN 978-3-319-31058-9
  • Online ISBN 978-3-319-31059-6
  • Series Print ISSN 2190-5053
  • Series Online ISSN 2190-5061
  • Buy this book on publisher's site
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