© 2016

The Neuropsychopathology of Schizophrenia

Molecules, Brain Systems, Motivation, and Cognition

  • Ming Li
  • William D. Spaulding

Part of the Nebraska Symposium on Motivation book series (NSM, volume 63)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Ming Li, Will Spaulding
    Pages 1-3
  3. William T. Carpenter, Katherine H. Frost, Kayla M. Whearty, Gregory P. Strauss
    Pages 133-158
  4. Gregory P. Strauss, Kayla M. Whearty, Katherine H. Frost, William T. Carpenter
    Pages 159-203
  5. Sarah E. Morris, Uma Vaidyanathan, Bruce N. Cuthbert
    Pages 225-252
  6. Back Matter
    Pages 253-257

About this book


One of the first major theoretical reviews of schizophrenia since the publication of the 5th edition of the APA’s Diagnostic and Statistical Manual, the DSM-5, this volume is a landmark in the history of schizophrenia research. It assembles recent groundbreaking developments in research on schizophrenia and reaffirms its central place in the mental health research agenda. Significantly, this volume reflects the paradigmatic shift in schizophrenia research applied in parallel to new approaches in psychiatric diagnosis. New models and findings from across disciplines in recent years reflect a new and greater understanding of the workings of the brain, which, in turn, helps develop our knowledge of the neuro and psychological processes in schizophrenia. Consequently, this volume illustrates a historical convergence of psychology, psychopathology and the neurosciences in schizophrenia.

World-renowned leaders of the schizophrenia research community in fields such as neuroscience,

psychiatry, neuropsychology, and clinical psychology offer clear suggestions for further advances in psychological and medical interventions, assessment, prevention strategies, and research. And in keeping with other titles in the Nebraska Symposium on Motivation series, these papers are noteworthy for their depth of detail, scientific rigor, and clinical relevance.

Included among the topics:

  • Cognitive organization as a dimension of individual differences and psychopathology.
  • Neurodevelopmental genomic strategies in the study of the psychosis spectrum.
  • Multimodal brain and behavior indices of psychosis risk.
  • The NIMH Research Domain Criteria Project: new approaches to classifying psychotic spectrum disorders.

The Neuropsychopathology of Schizophrenia is one of the most forward-thinking and engaging treatments of the field in recent years, and is an indispensable text for all researchers, academics, and clinicians who t

reat or

study mental illness, especially psychiatrists, psychologists, mental health practitioners, and neuroscientists specializing in schizophrenia.


The NIMH Research Domain Criteria Project avolition in schizophrenia biological information processing mechanisms cognitive dysfunction in schizophrenia genomic strategies in the study of psychosis mental health research agenda molecular processes of mental illness neural circuits and psychosis neuropharmacology neuroscience of schizophrenia psychosis risk brain biomarkers of psychosis genetic basis of schizophrenia negative symptons in schizophrenia individual differences and psychopathology

Editors and affiliations

  • Ming Li
    • 1
  • William D. Spaulding
    • 2
  1. 1.Department of PsychologyUniversity of Nebraska-LincolnLincolnUSA
  2. 2.Department of PsychologyUniversity of Nebraska-LincolnLincolnUSA

About the editors

Dr. Ming Li received his Bachelor and Master degrees in psychology from Beijing University in 1991 and 1996 respectively. After that, he went to the University of Toronto and studied under the supervision of Professor Alison Fleming on the neuroanatomical substrates of maternal memory in rats. He received his PhD in 2002. He then joined Professor Shitij Kapur's lab as a postdoctoral fellow at the Centre for Addiction and Mental Health, Toronto, and completed his postdoctoral training in 2005. Dr. Li joined the psychology faculty at the University of Nebraska-Lincoln in 2005. His research interests are focused in the field of behavioral pharmacology. Specifically, he is interested in developing animal models of schizophrenia, and understanding the neurobiological and behavioral mechanisms of action of antipsychotic drugs. His work is supported by the major federal and state funding agencies, and several research foundations.

Dr. Spaulding received his Ph.D. from the University of Arizona in 1976 and completed a postdoctoral Fellowship in Mental Health Research and Teaching at the University of Rochester, 1976-1979. He joined the UN-L faculty in 1979. His research interests address various aspects of schizophrenia and other severe disorders, including clinical and experimental psychopathology, the effectiveness of treatment and rehabilitation, and service systems and social policy. 

Bibliographic information

  • Book Title The Neuropsychopathology of Schizophrenia
  • Book Subtitle Molecules, Brain Systems, Motivation, and Cognition
  • Editors Ming Li
    William D. Spaulding
  • Series Title Nebraska Symposium on Motivation
  • Series Abbreviated Title Nebraska Sympos.Motivation
  • DOI
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Behavioral Science and Psychology Behavioral Science and Psychology (R0)
  • Hardcover ISBN 978-3-319-30594-3
  • Softcover ISBN 978-3-319-80844-4
  • eBook ISBN 978-3-319-30596-7
  • Series ISSN 0146-7875
  • Edition Number 1
  • Number of Pages IX, 257
  • Number of Illustrations 21 b/w illustrations, 18 illustrations in colour
  • Topics Neuropsychology
    Biological Psychology
  • Buy this book on publisher's site
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“This outstanding book, authored by leaders in psychosis research, is a very welcome addition to the psychiatric literature and is a testament to the current state of psychosis research. … This is a scholarly book that concludes each chapter with relevant and timely citations of the pertinent scientific literature. This is a superb book on the neuroscience of psychosis, particularly schizophrenia, that would be helpful for anyone interested in learning about the latest research on brain behavior relationships in psychosis.” (Michael Joel Schrift, Doody's Book Reviews, September, 2016)

“The papers in this volume are carefully conceived, clearly written, extensively referenced, highly informative, and forward-looking with respect to possible future research and clinical developments in the neuroscience of behavior. This book will be valued both by scholars in the field and by readers becoming initially familiar with neuroimaging methods and what they can reveal about brain–behavior relationships.” (Irving B. Weiner, PsycCRITIQUES, Vol. 61 (41), 2016)