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© 2016

Models of Calcium Signalling

Book

Part of the Interdisciplinary Applied Mathematics book series (IAM, volume 43)

Table of contents

  1. Front Matter
    Pages i-xxiii
  2. Basic Theory

    1. Front Matter
      Pages 1-1
    2. Geneviève Dupont, Martin Falcke, Vivien Kirk, James Sneyd
      Pages 3-27
    3. Geneviève Dupont, Martin Falcke, Vivien Kirk, James Sneyd
      Pages 29-96
    4. Geneviève Dupont, Martin Falcke, Vivien Kirk, James Sneyd
      Pages 97-161
    5. Geneviève Dupont, Martin Falcke, Vivien Kirk, James Sneyd
      Pages 163-205
    6. Geneviève Dupont, Martin Falcke, Vivien Kirk, James Sneyd
      Pages 207-242
  3. Specific Models

    1. Front Matter
      Pages 243-243
    2. Geneviève Dupont, Martin Falcke, Vivien Kirk, James Sneyd
      Pages 245-294
    3. Geneviève Dupont, Martin Falcke, Vivien Kirk, James Sneyd
      Pages 295-336
    4. Geneviève Dupont, Martin Falcke, Vivien Kirk, James Sneyd
      Pages 337-385
  4. Back Matter
    Pages 387-436

About this book

Introduction

This book discusses the ways in which mathematical, computational, and modelling methods can be used to help understand the dynamics of intracellular calcium. The concentration of free intracellular calcium is vital for controlling a wide range of cellular processes, and is thus of great physiological importance. However, because of the complex ways in which the calcium concentration varies, it is also of great mathematical interest.This book presents the general modelling theory as well as a large number of specific case examples, to show how mathematical modelling can interact with experimental approaches, in an interdisciplinary and multifaceted approach to the study of an important physiological control mechanism.

Geneviève Dupont is FNRS Research Director at the Unit of Theoretical Chronobiology of the Université Libre de Bruxelles;Martin Falcke is head of the Mathematical Cell Physiology group at the Max Delbrück Center for Molecular Medicine, Berlin;Vivien Kirk is an Associate Professor in the Department of Mathematics at the University of Auckland, New Zealand; James Sneyd is a Professor in the Department of Mathematics at The University of Auckland, New Zealand. 

Keywords

Calcium Dynamics Calcium Signaling Mathematical Modeling Nonlinear Dynamics Stochastic Modeling Calcium Signals and Waves Systems Biology Mathematical Physiology

Authors and affiliations

  1. 1.Unité de Chronobiologie ThéoriqueUniversite Libre de BruxellesBrusselsBelgium
  2. 2.MDCBerlinGermany
  3. 3.Department of MathematicsUniversity of AuklandAucklandNew Zealand
  4. 4.Department of MathematicsUniversity of AucklandAucklandNew Zealand

About the authors

Geneviève Dupont is Senior Research Associate at Universite Libre de Bruxelles. 
Martin Falcke is head of the Mathematical Cell Physiology group at the Max Delbruck Center for Molecular Medicine.

Vivien Kirk is Associate Professor of Mathematics at the University of Auckland.

James Sneyd is Professor of Mathematics at the University of Auckland.


Bibliographic information

  • Book Title Models of Calcium Signalling
  • Authors Geneviève Dupont
    Martin Falcke
    Vivien Kirk
    James Sneyd
  • Series Title Interdisciplinary Applied Mathematics
  • Series Abbreviated Title Interdisciplin. Appl. Math.
  • DOI https://doi.org/10.1007/978-3-319-29647-0
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Mathematics and Statistics Mathematics and Statistics (R0)
  • Hardcover ISBN 978-3-319-29645-6
  • Softcover ISBN 978-3-319-80616-7
  • eBook ISBN 978-3-319-29647-0
  • Series ISSN 0939-6047
  • Series E-ISSN 2196-9973
  • Edition Number 1
  • Number of Pages XXIII, 436
  • Number of Illustrations 114 b/w illustrations, 38 illustrations in colour
  • Topics Mathematical and Computational Biology
    Systems Biology
    Neurosciences
  • Buy this book on publisher's site

Reviews

“This book is entirely focused on the modelling aspects: how quantitative models of calcium signalling are constructed, ‘and how they can help build bridges between seemingly unrelated observations’ … . The book is intended for people who are familiar with the basic theory of differential equations. ... A selected list of literature for further productive reading on different levels of knowledge is given.” (Luisa Consiglieri, zbMATH 1350.92002, 2017)