© 2016

Dental Stem Cells

  • Fikrettin Şahin
  • Ayşegül Doğan
  • Selami Demirci

Part of the Stem Cell Biology and Regenerative Medicine book series (STEMCELL)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Pakize Neslihan Taşlı, Safa Aydın, Fikrettin Şahin
    Pages 29-45
  3. Sukru Gulluoglu, Emre Can Tuysuz, Omer Faruk Bayrak
    Pages 47-67
  4. Genxia Liu, Shu Ma, Yixiang Zhou, Yadie Lu, Lin Jin, Zilu Wang et al.
    Pages 69-92
  5. Valeriya V. Solovyeva, Andrey P. Kiyasov, Albert A. Rizvanov
    Pages 93-107
  6. Irina Kerkis, Cristiane V. Wenceslau, Celine Pompeia
    Pages 125-141
  7. Arash Khojasteh, Pantea Nazeman, Maryam Rezai Rad
    Pages 143-165
  8. Sema S. Hakki, Erdal Karaoz
    Pages 167-196
  9. Zhipeng Fan, Xiao Lin
    Pages 197-216
  10. Annelies Bronckaers, Esther Wolfs, Jessica Ratajczak, Petra Hilkens, Pascal Gervois, Ivo Lambrichts et al.
    Pages 217-241
  11. Nareshwaran Gnanasegaran, Vijayendran Govindasamy, Prakash Nathan, Sabri Musa, Noor Hayaty Abu Kasim
    Pages 243-268
  12. Naohisa Wada, Atsushi Tomokiyo, Hidefumi Maeda
    Pages 289-307
  13. Back Matter
    Pages 309-317

About this book


This book explores dental stem cell (DSC) biology, from a review of basic concepts for cell culture, to isolation, self-renewal, multipotency and differentiation, regulation by molecular medicine, and prospective research areas for regenerative medicine. The first seven chapters delve into basic DSC properties, vital signaling pathways involved in differentiation, pluripotency, iPS cell development from DSCs, and genetic engineering approaches of DSCs in accordance with the current literature. A comprehensive review of possible clinical applications and in vitro/in vivo studies follows, illustrating the future of DSC research for in the tissue engineering field. The text also discusses the political, ethical, social, and legal ramifications of the use of dental stem cells.

Expertly authored and drawing from a multitude of international perspectives, Dental Stem Cells is an invaluable addition to Springer's Stem Cell Biology and Regenerative Medicine series. It is essential reading for advanced graduate students, basic researchers, and clinical investigators in the fields of stem cell therapy, biological sciences of dentistry, and regenerative medicine.


bone tissue craniofacial regeneration mesenchymal progenitor cells bio-tooth angiogenesis

Editors and affiliations

  • Fikrettin Şahin
    • 1
  • Ayşegül Doğan
    • 2
  • Selami Demirci
    • 3
  1. 1.Yeditepe UniversityGenetics and Bioengineering DepartmentIstanbulTurkey
  2. 2.Yeditepe UniversityGenetics and Bioengineering DepartmentIstanbulTurkey
  3. 3.Yeditepe UniversityGenetics and Bioengineering DepartmentISTANBULTurkey

About the editors

Fikrettin Şahin received his PhD from the College of Food, Agricultural and Environmental Sciences, The Ohio State University, Columbus, Ohio. After completing his postdoctoral research at the same university and at the Pest Management Research Centre of Agriculture and Agri-Food Canada, he worked as an assistant professor in the Department of Plant Pathology, Ataturk University, in Erzurum, Turkey. Dr. Sahin is now a professor and chair of the Department of Genetics and Bioengineering, Yeditepe University, İstanbul, Turkey. He is on the advisory board of several journals, a member of the Technology and Inonvation Support Programme (TEYDEP), a principal member of The Turkish Academy of Sciences, and many other prestigious scientific committees and initiatives. Prolifically and internationally published, Dr. Sahin’s research focuses on dental stem cells in the contexts of isolation, maintenance, differentiation and possible use for particular regenerative approaches. His other research areas include  molecular microbiology, phytopathology, stem cell and gene therapy, and cancer.   

Ayşegül Doğan received her PhD from Yeditepe University in Istanbul, Turkey, where she is a postdoctoral researcher in the Department of Genetics and Bioengineering. She works with the Gene and Cell Therapy group at the University’s Molecular Diagnostic Laboratory, and is a member of stem cell and cellular therapy societies in Turkey. Her research focuses on mesenchymal stem cells, gene and cell therapy, cancer and wound healing. Dr. Doğan is currently working with dental stem cells obtained from wisdom teeth of young adults and the potential use of these cells in gene and stem cell therapy applications. 

Selami Demirci received his PhD from the department of Genetics and Bioengineering at the University of Yeditepe in Istanbul, Turkey. He is currently a Research fellow at the same department. Dr. Demirci is a member of the Stem Cell and Cellular Therapies Society, Turkey, and has completed several projects on dental stem cell maintenance and differentiation towards desired cell lineages for a particular regeneration approaches. His ongoing studies includes gene functions in stem cell, wound healing and regenerative medicine.   

Bibliographic information

  • Book Title Dental Stem Cells
  • Editors Fikrettin Şahin
    Ayşegül Doğan
    Selami Demirci
  • Series Title Stem Cell Biology and Regenerative Medicine
  • Series Abbreviated Title Stem Cell Biology,Regenerative Med.
  • DOI
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-3-319-28945-8
  • Softcover ISBN 978-3-319-80461-3
  • eBook ISBN 978-3-319-28947-2
  • Series ISSN 2196-8985
  • Series E-ISSN 2196-8993
  • Edition Number 1
  • Number of Pages XIII, 317
  • Number of Illustrations 0 b/w illustrations, 30 illustrations in colour
  • Topics Stem Cells
    Regenerative Medicine/Tissue Engineering
  • Buy this book on publisher's site
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