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© 2016

Metallothioneins in Normal and Cancer Cells

Book

Part of the Advances in Anatomy, Embryology and Cell Biology book series (ADVSANAT, volume 218)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Piotr Dziegiel, Bartosz Pula, Christopher Kobierzycki, Mariusz Stasiolek, Marzenna Podhorska-Okolow
    Pages 1-2
  3. Piotr Dziegiel, Bartosz Pula, Christopher Kobierzycki, Mariusz Stasiolek, Marzenna Podhorska-Okolow
    Pages 3-20
  4. Piotr Dziegiel, Bartosz Pula, Christopher Kobierzycki, Mariusz Stasiolek, Marzenna Podhorska-Okolow
    Pages 21-27
  5. Piotr Dziegiel, Bartosz Pula, Christopher Kobierzycki, Mariusz Stasiolek, Marzenna Podhorska-Okolow
    Pages 29-63
  6. Piotr Dziegiel, Bartosz Pula, Christopher Kobierzycki, Mariusz Stasiolek, Marzenna Podhorska-Okolow
    Pages 65-77
  7. Back Matter
    Pages 79-117

About this book

Introduction

This book describes the structures of Metallothionein (MT) family members and the cellular functions of MT-1, MT-2 and MT-4 isoforms, as well as provides insights into divergent biological roles of MT-3. The authors explain the involvement of MT molecules in various processes related to carcinogenesis, including an organ-specific presentation of current data concerning their potential impact on the progression of various tumors and the regulatory role of MT family members in the function of the immune system. 

Keywords

cell senescence progression intracellular zinc homeostasis toxic metal detoxification growth inhibitory factor neurodegeneration

Authors and affiliations

  1. 1.Dept. of Histology and EmbryologyWroclaw Medical UniversityWroclawPoland
  2. 2.Department of Histology and EmbryologyWroclaw Medical UniversityWroclawPoland
  3. 3.Dept. of Histology and EmbryologyWroclaw Medical UniversityWroclawPoland
  4. 4.Polish Mother's Mem. Hospital Res. Inst.Dept. of NeurologyLodzPoland
  5. 5.Dept. of Histology and EmbryologyWroclaw Medical UniversityWroclawPoland

Bibliographic information

  • Book Title Metallothioneins in Normal and Cancer Cells
  • Authors Piotr Dziegiel
    Bartosz Pula
    Christopher Kobierzycki
    Mariusz Stasiolek
    Marzenna Podhorska-Okolow
  • Series Title Advances in Anatomy, Embryology and Cell Biology
  • Series Abbreviated Title Advs Anatomy
  • DOI https://doi.org/10.1007/978-3-319-27472-0
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Softcover ISBN 978-3-319-27471-3
  • eBook ISBN 978-3-319-27472-0
  • Series ISSN 0301-5556
  • Series E-ISSN 2192-7065
  • Edition Number 1
  • Number of Pages XII, 117
  • Number of Illustrations 2 b/w illustrations, 11 illustrations in colour
  • Topics Cell Biology
    Immunology
    Cancer Research
  • Buy this book on publisher's site
Industry Sectors
Biotechnology
Health & Hospitals
Pharma

Reviews

“This is a concise monograph on the pathophysiological role of molecules called metallothioneins in cancerous cells including GI, GU, renal, endocrine, and CNS systems. Normal physiology of these compounds is described well. The biochemical pathways, signal transduction, and cellular mechanisms are discussed in depth. … I recommend this book to those interested in physiology and cancer research. Students, fellows and experts will all find this reference beneficial.” (Joseph J. Grenier, Amazon.com, June, 2016)