© 2016

Modified Nucleic Acids

  • Kazuhiko Nakatani
  • Yitzhak Tor

Part of the Nucleic Acids and Molecular Biology book series (NUCLEIC, volume 31)

Table of contents

  1. Front Matter
    Pages i-x
  2. Andrea Fin, Alexander R. Rovira, Patrycja A. Hopkins, Yitzhak Tor
    Pages 1-26
  3. Yoshio Saito, Azusa Suzuki, Isao Saito
    Pages 27-61
  4. Christian Schwechheimer, Marcus Merkel, Peggy R. Bohländer, Hans-Achim Wagenknecht
    Pages 83-100
  5. Tadao Takada, Mitsunobu Nakamura, Kazushige Yamana
    Pages 101-121
  6. Jitka Dadová, Hana Cahová, Michal Hocek
    Pages 123-144
  7. Takashi Sakamoto, Kenzo Fujimoto
    Pages 145-157
  8. Sandip A. Shelke, Snorri Th. Sigurdsson
    Pages 159-187
  9. Yoshiyuki Hari, Satoshi Obika
    Pages 209-219
  10. Michiko Kimoto, Ken-ichiro Matsunaga, Yushi T. Redhead, Ichiro Hirao
    Pages 249-268
  11. Back Matter
    Pages 269-276

About this book


This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases.
Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book addresses new developments and is designed for graduate level and professional research purposes.


Pyrimidine and purine analogs Electron paramagnetic resonance (EPR) spectroscopy Emission paramagnetic resonance spectroscopy Double-stranded DNA Unnatural nucleic acids Base pair creation Nucleobases

Editors and affiliations

  • Kazuhiko Nakatani
    • 1
  • Yitzhak Tor
    • 2
  1. 1.The Institute of Scientific and IndustriOsaka UniversityIbaraki, OsakaJapan
  2. 2.University of California, San DiegoLa JollaUSA

Bibliographic information

  • Book Title Modified Nucleic Acids
  • Editors Kazuhiko Nakatani
    Yitzhak Tor
  • Series Title Nucleic Acids and Molecular Biology
  • Series Abbreviated Title Nucleic Acids,Molec.Biology
  • DOI
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-3-319-27109-5
  • Softcover ISBN 978-3-319-80076-9
  • eBook ISBN 978-3-319-27111-8
  • Series ISSN 0933-1891
  • Series E-ISSN 1869-2486
  • Edition Number 1
  • Number of Pages X, 276
  • Number of Illustrations 100 b/w illustrations, 62 illustrations in colour
  • Topics Nucleic Acid Chemistry
    Cell Biology
    Biochemical Engineering
  • Buy this book on publisher's site
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