The Mathematics and Biology of the Biodistribution of Radiopharmaceuticals - A Clinical Perspective

  • William C Klingensmith III

Table of contents

  1. Front Matter
    Pages i-xv
  2. Introductory Concepts

    1. Front Matter
      Pages 1-1
    2. William C. Klingensmith III
      Pages 3-13
    3. William C. Klingensmith III
      Pages 15-26
  3. Mathematics of the Biodistribution of Radiopharmaceuticals

    1. Front Matter
      Pages 27-27
    2. William C. Klingensmith III
      Pages 33-49
    3. William C. Klingensmith III
      Pages 51-59
    4. William C. Klingensmith III
      Pages 61-73
    5. William C. Klingensmith III
      Pages 75-88
    6. William C. Klingensmith III
      Pages 89-98
    7. William C. Klingensmith III
      Pages 99-112
    8. William C. Klingensmith III
      Pages 113-125
  4. Quantitative Evaluation in Nuclear Medicine Studies

    1. Front Matter
      Pages 127-127
    2. William C. Klingensmith III
      Pages 139-160
    3. William C. Klingensmith III
      Pages 161-175
    4. William C. Klingensmith III
      Pages 177-186
    5. William C. Klingensmith III
      Pages 187-202
    6. William C. Klingensmith III
      Pages 203-222

About this book

Introduction

This book explores the mathematics and biology of the biodistribution of radiopharmaceuticals following their introduction into the body, but does so primarily from a clinical perspective – from the point of view of image interpretation and any associated image-derived quantification. All of the equations included in the book relate directly to the biodistribution of radiopharmaceuticals and are clinically useful, either conceptually or because of their value in quantifying a biological parameter, e.g., renal clearance. In particular, the more complex equations are not meant to be solved but instead are intended to provide a conceptual basis for the analysis of clinical images, especially those that are unusual and/or difficult to interpret. The efficacy of every diagnostic and therapeutic nuclear medicine procedure is critically dependent on the biodistribution of the radiopharmaceutical in question over time. This book will enable the reader to gain a sound understanding of the relevant mathematics and biology, and the clinical orientation ensures that it will be of value in enhancing clinical practice.

Keywords

Image Interpretation in Radiology Image-derived Quantification Mathematics of Nuclear Medicine Nuclear Medicine Nuclear Medicine Physics Quantitative Evaluation in Nuclear Medicine Studies Radiopharmacology

Authors and affiliations

  • William C Klingensmith III
    • 1
  1. 1.Cherry Hills VillageUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-26704-3
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-26702-9
  • Online ISBN 978-3-319-26704-3
  • About this book
Industry Sectors
Pharma