© 2016

Pediatric Continuous Renal Replacement Therapy

Principles and Practice


Table of contents

  1. Front Matter
    Pages i-xiv
  2. Farahnak Assadi, Fatemeh Ghane Sharbaf
    Pages 1-34
  3. Farahnak Assadi, Fatemeh Ghane Sharbaf
    Pages 35-40
  4. Farahnak Assadi, Fatemeh Ghane Sharbaf
    Pages 41-70
  5. Farahnak Assadi, Fatemeh Ghane Sharbaf
    Pages 71-97
  6. Farahnak Assadi, Fatemeh Ghane Sharbaf
    Pages 99-120
  7. Farahnak Assadi, Fatemeh Ghane Sharbaf
    Pages 121-143
  8. Back Matter
    Pages 145-158

About this book


This book provides a current understanding of Continuous Renal Replacement Therapies (CRRT) techniques with a focus on drug dosing in critically ill children receiving CRRT.  Strategies include the role of therapeutic drug monitoring, effect of CRRT on drug pharmacokinetics, variations in the drugs properties, newer kidney injury biomarkers and simple and easy methods for estimating drug clearance.  The conclusion of this book features case reports focused on the patients’ symptoms and laboratory data as they present in clinical practice and the type of CRRT modality needed to provide quality, safety, and cost-effectiveness of patient care.  Pediatric Continuous Renal Replacement Therapy will expand the clinical knowledge and experience of practicing nephrologists and other professionals involved in the care of children suffering from Acute Kidney Injury (AKI) to improve and sustain their quality of life.


Pediatric Continuous Renal Replacement Therapy CRRT Acute kidney injury AKI Hemodialysis Vascular Access Dialysis and blood flow rates Drug pharmacokinetics Creatinine clearance

Authors and affiliations

  1. 1.Rush University Medical CenterUSA
  2. 2.Mashad University of Medical SciencesIran

About the authors

Farahnak Assadi, M.D.

Distinguished Professor, Emeritus 

Department of Pediatrics

Rush University Medical College

Division of Nephrology

Rush Children's Hospital

Chicago, Illinois


Fatemeh Ghane Sharbaf, M.D. 

Associate Professor

Department of Pediatrics 

Section of Nephrology 

Mashhad University of Medical Sciences

Mashhad, Iran

Bibliographic information

  • Book Title Pediatric Continuous Renal Replacement Therapy
  • Book Subtitle Principles and Practice
  • Authors Farahnak Assadi
    Fatemeh Sharbaf
  • DOI
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-3-319-26201-7
  • Softcover ISBN 978-3-319-79905-6
  • eBook ISBN 978-3-319-26202-4
  • Edition Number 1
  • Number of Pages XIV, 158
  • Number of Illustrations 10 b/w illustrations, 0 illustrations in colour
  • Topics Nephrology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology


“The book is written for residents and practitioners in pediatric critical care and nephrology. … It covers acute kidney injury, pharmacology of drugs in acute kidney injury, and continuous renal replacement therapy modalities.” (Aftab Chishti, Doody's Book Reviews, September, 2017)

“An updated practical guide for the treatment of acute kidney injury with didactic illustrations and tables. For pediatric nephrologists.” (Zvi Laron, Pediatric Endocrinology Reviews, Vol. 13 (4), June, 2016)