© 2015

Emerging and Evolving Topics in Multiple Sclerosis Pathogenesis and Treatments

  • Anne C. La Flamme
  • Jacqueline Monique Orian
  • This book highlights the areas that have been most revised by recent discoveries relevant to the treatment, diagnosis, or basic understanding of the underlying pathobiology of Multiple Sclerosis

  • This book creates linkages between the clinical and basic science aspect

  • Covers areas of interest to clinicians as well as basic scientists, and thus appeals to a broad readership


Part of the Current Topics in Behavioral Neurosciences book series (CTBN, volume 26)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Shannon E. Dunn, Hyunwoo Lee, Farzan Rusi Pavri, Monan Angela Zhang
    Pages 29-56
  3. Anna Karin Hedström, Tomas Olsson, Lars Alfredsson
    Pages 87-104
  4. Julia Pakpoor, Sreeram Ramagopalan
    Pages 105-115
  5. Felix Marsh-Wakefield, Scott N. Byrne
    Pages 117-141
  6. Phuc T. Dang, Quyen Bui, Claretta S. D’Souza, Jacqueline M. Orian
    Pages 143-177
  7. Sharmilee Gnanapavan, Gavin Giovannoni
    Pages 179-194
  8. Radu Tanasescu, Cris S. Constantinescu
    Pages 195-220
  9. Michael P. Kurnellas, Jonathan B. Rothbard, Lawrence Steinman
    Pages 221-232
  10. Back Matter
    Pages 233-235

About this book


Over the past decade, we have made great advances in the field of multiple sclerosis (MS) research, and this book focuses on those advances in MS pathogenesis and treatment. While some of these advances have been through new approaches and ideas that have emerged in the last decade such as the newly identified protective role that amyloid proteins may play in MS or the use of helminths to treat autoimmune diseases, others have evolved from previous theories and ideas that have only now gained momentum and a deeper understanding such as the role of HLA or gender in MS susceptibility. This book covers these emerging and evolving topics and highlights the substantial advancements made in elucidation of the factors regulating susceptibility or disease progression, identification of new ways to monitor or predict MS pathology, and development of new strategies for treating MS.


Emerging therapeutic approaches and targets Epidemiology of MS Multiple sclerosis disease assessment Neuroimaging Neuroinflammation Psychoneuroimmunology

Editors and affiliations

  • Anne C. La Flamme
    • 1
  • Jacqueline Monique Orian
    • 2
  1. 1.School of Biological Sciences, Malaghan Institute of Medical ResearchVictoria University of Wellington School of Biological SciencesWellingtonNew Zealand
  2. 2.Department of BiochemistrySchool of Molecular Sciences La Trobe Institute for Molecular ScienceMelbourneAustralia

Bibliographic information

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