© 2016

Hepatic De Novo Lipogenesis and Regulation of Metabolism

  • James M. Ntambi

Table of contents

  1. Front Matter
    Pages i-xi
  2. Sophie C. Cazanave, Arun J. Sanyal
    Pages 101-129
  3. Mohamed Amine Lounis, Sabri Rial, James M. Ntambi, Catherine Mounier
    Pages 143-164
  4. Yumi Imai, Michelle B. Trevino, Rexford S. Ahima
    Pages 165-188
  5. Vishal Singh, Beng San Yeoh, James M. Ntambi, Matam Vijay-Kumar
    Pages 189-209
  6. Shih-Lung Woo, Ting Guo, Chaodong Wu
    Pages 211-234
  7. David Jacobi, Hyunjii J. Cho, Ryan K. Alexander, Chih-Hao Lee
    Pages 235-253
  8. Ludger Scheja, Christoph Buettner
    Pages 267-283
  9. Sonia M. Najjar
    Pages 285-295
  10. Back Matter
    Pages 297-305

About this book


The liver is the largest solid vital organ in mammals that supports other organ in the body in some facet.  This book synthesizes all the primary and relevant metabolic information that one needs to review to understand the complex and diverse role of the liver in metabolism.

With the current epidemic of metabolic diseases, it is of immediate importance to understand the contribution of the liver in health and its role in the development of impaired metabolic regulation. This book covers the many studies that have unmasked important roles that proteins expressed in the liver play in the development of or protection from metabolic diseases.

One of the major metabolic functions of the liver is to carry out de novo lipogenesis, which is the metabolic pathway that allows the conversion of excess carbohydrates into fatty acids. The process of de novo lipogenesis is covered in depth within this volume.  The book is an important contribution to the vast literature and ongoing research on liver function.


De novo lipogenesis Obesity liver steatosis inflammation insulin resistance lipogenesis FoxO1-A

Editors and affiliations

  • James M. Ntambi
    • 1
  1. 1.Departments of Biochemistry and Nutritional SciencesUniversity of Wisconsin-MadisonMadisonUSA

About the editors

James M. Ntambi, PhD, is the Katherine Berns Von Donk Steenbock Professor in Nutrition, Department of Chemistry, College of Agricultural and Life Sciences, at the University of Wisconsin, Madison.

Bibliographic information

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