Epigenetic Advancements in Cancer

  • Manoj K. Mishra
  • Kumar S. Bishnupuri

Table of contents

  1. Front Matter
    Pages i-xi
  2. Rajesh Singh, James W. Lillard Jr., Shailesh Singh
    Pages 27-63
  3. James A. Stokes III, Sanjay Kumar, Karyn Scissum-Gunn, Udai P. Singh, Manoj K. Mishra
    Pages 65-78
  4. Kumar S. Bishnupuri, Manoj K. Mishra
    Pages 97-121
  5. Rashmi K. Ambasta, Dhiraj Kumar, Piyush Sawhney, Rajat Gupta, Parul Yadav, Pooja Pabari et al.
    Pages 123-144
  6. Niraj Kumar Jha, Saurabh Kumar Jha, Satyaprakash, Rohan Kar, Deepak Rathore, Rashmi K. Ambasta et al.
    Pages 145-176
  7. Ankit Tripathi, Renu Sharma, Noopur Kejriwal, Rashmi K. Ambasta, Pravir Kumar
    Pages 177-205
  8. Gulistan Mese, Ozden Yalcin-Ozuysal
    Pages 207-228
  9. Sanjay Kumar, James A. Stokes III, Udai P. Singh, Kumar S. Bishnupuri, Manoj K. Mishra
    Pages 229-244
  10. Back Matter
    Pages 245-246

About this book

Introduction

This volume explores the epigenetic alterations and their association with various human cancers. Considering one of human cancer as an example, individual chapters are focused on defining the role of epigenetic regulators and underlying mechanisms in cancer growth and progression.
 
Epigenetic alteration including DNA methylation, histone modification, nucleosome positioning and non-coding RNAs expression are involved in a complex network of regulating expression of oncogenes and tumor suppressor genes and constitute an important event of the multistep process of carcinogenesis. Recent advances in the understanding of the epigenetic regulation and detailed information of these epigenetic changes in various cancers provide new avenues of advancements in diagnostics, prognostics, and therapies of this highly fatal disease.

Keywords

DNA methylation Gene-expression control Histone modifications RNA expression Epigenetic regulators

Editors and affiliations

  • Manoj K. Mishra
    • 1
  • Kumar S. Bishnupuri
    • 2
  1. 1.Department of Biological SciencesAlabama State UniversityMontgomeryUSA
  2. 2.School of MedicineWashington UniversitySt. LouisUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-24951-3
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-24949-0
  • Online ISBN 978-3-319-24951-3
  • About this book
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