© 2016

Short Course Breast Radiotherapy

A Comprehensive Review of Hypofractionation, Partial Breast, and Intra-Operative Irradiation

  • Douglas W Arthur
  • Frank A. Vicini
  • David E. Wazer
  • Atif J. Khan

Table of contents

  1. Front Matter
    Pages i-ix
  2. Background and Supporting Concepts

    1. Front Matter
      Pages 1-1
    2. Atif J. Khan, Alexandra Stewart, Roger Dale
      Pages 39-52
    3. Bruce Thomadsen, Rupak Das
      Pages 53-75
    4. Nayana L. Vora, Sharon L. Clancy, Richard D. Pezner
      Pages 97-104
    5. Matthew E. Schutzer, Noah S. Kalman, Sewit Teckie, Louis Potters
      Pages 105-118
  3. Hypofractionated Whole Breast Irradiation

    1. Front Matter
      Pages 119-119
    2. Kristofer Kainz, X. Allen Li
      Pages 137-152
    3. Onyinye Balogun, Silvia Formenti
      Pages 153-167
    4. Julie Arsenault, Timothy Whelan
      Pages 169-180
  4. Accelerated Partial Breast Irradiation

    1. Front Matter
      Pages 195-195
    2. Dorin A. Todor
      Pages 207-227
    3. Chirag Shah, Shireen Parsai, Rupesh Kotecha, Rahul Tendulkar, Frank A. Vicini
      Pages 229-244

About this book


This comprehensive handbook on the implementation of short course radiotherapy for the treatment of breast cancer is intended as an up-to-date resource for the clinician. The book opens with a series of chapters on underlying principles and diverse relevant topics, including pathologic anatomy of early-stage breast cancer, radiobiology of accelerated breast irradiation, quality assurance and radiation safety, surgical considerations in partial breast irradiation, and impact of oncoplastic surgery on adjuvant radiotherapy. Individual sections are then devoted to hypofractionated whole breast radiotherapy, accelerated partial breast irradiation, and intraoperative radiotherapy. Each section includes details of patient selection, physics, techniques, data, and toxicity.  The reader is provided with clear guidance on the appropriate use of accelerated forms of adjuvant radiotherapy for treatment of early-stage breast cancer and on various emerging treatment approaches.


3D-Conformal external beam radiotherapy Accelerated Breast Irradiation Breast Cancer Breast Radiation Oncology Extreme hypofractionation Interstitial brachytherapy Non-invasice Breast Brachytherapy Partial Breast Irradiation Pre-operative radiotherapy

Editors and affiliations

  • Douglas W Arthur
    • 1
  • Frank A. Vicini
    • 2
  • David E. Wazer
    • 3
  • Atif J. Khan
    • 4
  1. 1.Department of Radiation OncologyVirginia Commonwealth Univ Sch. Medicine Department of Radiation OncologyRICHMONDUSA
  2. 2.Michigan Healthcare Professionals21st Century Oncology Michigan Healthcare ProfessionalsFarmington HillsUSA
  3. 3.Dept. Rad Oncol, Tufts Univ. School MedAlpert Medical School Brown University Dept. Rad Oncol, Tufts Univ. School MedBOSTONUSA
  4. 4.Dept. of Radiation OncologyRutgers Can State Univ. New Jer Sch. Med Dept. of Radiation OncologyNEW BRUNSWICKUSA

About the editors

Dr. Arthur is currently Professor and Vice Chairman of the  Department of Radiation Oncology , Virginia Commonwealth University. His clinical and research interests include brachytherapy, management of breast and genitourinary malignancies, and soft tissue malignancies. Dr Arthur’s primary research interests include clinical studies focusing on the treatment of breast cancer with special interest in the development and use of accelerated treatment for breast cancer.  He is a breast committee member of the NRG Oncology national cooperative trial group.  

Dr. Frank Vicini has held multiple academic appointments and authored over 200 peer-reviewed articles. He is involved in numerous clinical studies being the Principal Investigator of several with the goal of improving therapeutic outcomes for all stages of breast cancer, reducing cancer treatment times and minimizing toxicities of healthy tissues and vital organs. He is also listed as one of the few oncologists in "Best Oncology Doctors in America."

David E. Wazer, MD is chief of radiation oncology for the Lifespan Healthcare System in New England and divides his time between Rhode Island Hospital and Tufts Medical Center in Boston. He is professor and chairman of radiation oncology at both Tufts University School of Medicine and The Alpert Medical School of Brown University. Dr. Wazer has numerous sc

ientific publications, co-edits the premier textbook for radiation oncology,  serves as Editor-in-Chief of the American Journal of Clinical Oncology, and actively conducts clinical and cost/utility research in breast cancer, brachytherapy, melanoma, and several novel radiation therapy technologies. 

Dr. Khan has been at the Cancer Institute of New Jersey since 2007 after completing a fellowship in brachytherapy at the Brigham and Women’s Hospital at Harvard. Prior to that, he completed a residency in radiation oncology at Rush University Medical Center. Dr. Khan’s primary focus has been in breast cancer, as well as radiation therapy for central nervous system/brain tumors.  Dr Khan is interested in the discovery of novel radiosensitizers and in advanced modalities of highly conformal radiotherapy, such as image-guided brachytherapy and proton therapy.   

Bibliographic information

  • Book Title Short Course Breast Radiotherapy
  • Book Subtitle A Comprehensive Review of Hypofractionation, Partial Breast, and Intra-Operative Irradiation
  • Editors Douglas W Arthur
    Frank A. Vicini
    David E. Wazer
    Atif J. Khan
  • DOI
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-3-319-24386-3
  • Softcover ISBN 978-3-319-79617-8
  • eBook ISBN 978-3-319-24388-7
  • Edition Number 1
  • Number of Pages IX, 501
  • Number of Illustrations 34 b/w illustrations, 109 illustrations in colour
  • Topics Radiotherapy
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology


“It is sometimes good to take stock of a situation and of the four major issues in breast radio therapy viz. hypofractionation, partial breast radiation, intraoperative radio therapy and extent of nodal radiation. The first three are comprehensively reviewed in this excellent and well referenced book. … Overall an excellent book for the shelves of every evidenced base breast radiation oncologist.” (Dr. Nick Plowman, RAD Magazine, September, 2016)