Lung Cancer and Personalized Medicine

Current Knowledge and Therapies

  • Aamir Ahmad
  • Shirish Gadgeel

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 893)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Lindsey A. Torre, Rebecca L. Siegel, Ahmedin Jemal
    Pages 1-19
  3. Ann G. Schwartz, Michele L. Cote
    Pages 21-41
  4. Gabriel Alberto Rivera, Heather Wakelee
    Pages 43-57
  5. Lysanne Lievense, Joachim Aerts, Joost Hegmans
    Pages 59-90
  6. Stefano Cafarotti, Filippo Lococo, Patrizia Froesh, Francesco Zappa, Dutly Andrè
    Pages 127-136
  7. Jarushka Naidoo, Alexander Drilon
    Pages 155-178
  8. Sai-Hong Ignatius Ou, Keisuke Shirai
    Pages 179-187
  9. Eric S. Kim
    Pages 189-209
  10. Back Matter
    Pages 225-228

About this book


This, the first of two volumes on personalized medicine in lung cancer, touches on the core issues related to the understanding of lung cancer—statistics and epidemiology of lung cancer—along with the incidence of lung cancer in non-smokers. A major focus of this volume is the state of current therapies against lung cancer—immune, targeted therapies against EGFR TKIs, KRAS, ALK, angiogenesis; the associated challenges, especially resistance mechanisms; and recent progress in targeted drug development based on metal chemistry. Chapters are written by some of the leading experts in the field, who provide a better understanding of lung cancer, the factors that make it lethal, and current research focused on developing personalized treatment plans. With a unique mix of topics, this volume summarizes the current state-of-knowledge on lung cancer and the available therapies.


ALK signaling EGFR signaling k-ras lung cancer therapy personalized therapy small cell lung cancer

Editors and affiliations

  • Aamir Ahmad
    • 1
  • Shirish Gadgeel
    • 2
  1. 1.Wayne State University, Karmanos Cancer InstituteDetroitUSA
  2. 2.Wayne State University, Karmanos Cancer InstituteDetroitUSA

Bibliographic information

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