Cancer Stem Cells: Emerging Concepts and Future Perspectives in Translational Oncology

  • Sadegh Babashah

Table of contents

  1. Front Matter
    Pages i-xxx
  2. The Biology of Cancer Stem Cells

    1. Front Matter
      Pages 1-1
    2. Katayoon Pakravan, Mohammad Amin Mahjoub, Babak Jahangiri, Sadegh Babashah
      Pages 3-11
    3. Paola Ferrari, Andrea Nicolini
      Pages 13-66
    4. Clifford Liongue, Alister C. Ward, Wei Duan, Sarah Shigdar
      Pages 67-87
    5. Claudia Peitzsch, Monica Cojoc, Ina Kurth, Anna Dubrovska
      Pages 89-130
    6. Ryou-u Takahashi, Hiroaki Miyazaki, Takahiro Ochiya
      Pages 131-153
    7. Lu Deng, Jiahui Xu, Dong Wang, Suling Liu
      Pages 155-174
  3. Cancer Stem Cells in Human Malignancies

    1. Front Matter
      Pages 175-175
    2. Giorgia G. Silveira, Joao Paulo Oliveira-Costa, Alfredo Ribeiro-Silva
      Pages 177-197
    3. Gavitt A. Woodard, David M. Jablons
      Pages 199-225
    4. Pratima Nangia-Makker, Yingjie Yu, Lulu Farhana, Kulsoom Ahmed, Adhip P. N. Majumdar
      Pages 227-245
    5. Deepak Ray, Reyhaneh Khoshchehreh, Alexandra Aicher, Christopher Heeschen
      Pages 247-271
    6. Luca Persano, Alessandro Della Puppa, Elena Porcù, Francesca Maule, Giampietro Viola
      Pages 273-296
    7. Chiara Bianchini, Andrea Ciorba
      Pages 297-305
    8. Michael W. Becker, Kristen M. O’Dwyer
      Pages 307-332
  4. Novel Approaches for Targeting Cancer Stem Cells

    1. Front Matter
      Pages 391-391
    2. Krysta M. Coyle, Margaret L. Thomas, Mohammad Sultan, Paola Marcato
      Pages 393-443
    3. Alice Turdo, Matilde Todaro, Giorgio Stassi
      Pages 445-476
    4. Margaret L. Thomas, Krysta M. Coyle, Mohammad Sultan, Paola Marcato
      Pages 477-518
    5. Aadel A. Chaudhuri, Michael S. Binkley, Maximilian Diehn
      Pages 519-531
    6. Chunguang Yang, Kunlin Jin, Yue Zhang, Hong Sun, William C. Cho
      Pages 533-553
  5. Back Matter
    Pages 555-560

About this book


The concept of cancer stem cells has great clinical implications. This is due to the fact that small subpopulations of these cells have been identified in a variety of neoplastic conditions ranging from solid tumors to liquid malignancies. Although there are some huge gaps in our current understanding of the role played by cancer stem cells in cancer biology, a growing body of evidence provides strong support for the principal functions of these cells in tumorigenesis. This has represented the potential of cancer stem cells in the development of novel and innovative tools for the treatment of metastatic tumors. This book aims to offer a broad framework for obtaining insight into the state-of-the-art knowledge on cancer stem cell biology and highlight the therapeutic implications of these cells in the future of clinical oncology.


Cancer stem cells Chemoresistance Stem cell pathways Therapy Translational studies

Editors and affiliations

  • Sadegh Babashah
    • 1
  1. 1.Faculty of Biol. Scs. Dept. of Mol. Gen.Tarbiat Modares University TehranIran

Bibliographic information

Industry Sectors
Health & Hospitals
Oncology & Hematology
Consumer Packaged Goods