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Sertoli Cell Metabolism and Spermatogenesis

  • Pedro F. Oliveira
  • Marco G. Alves

Part of the SpringerBriefs in Cell Biology book series (SBCB)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Pedro F. Oliveira, Marco G. Alves
    Pages 1-2
  3. Pedro F. Oliveira, Marco G. Alves
    Pages 3-13
  4. Pedro F. Oliveira, Marco G. Alves
    Pages 15-24
  5. Pedro F. Oliveira, Marco G. Alves
    Pages 25-39
  6. Pedro F. Oliveira, Marco G. Alves
    Pages 41-56
  7. Pedro F. Oliveira, Marco G. Alves
    Pages 57-71
  8. Pedro F. Oliveira, Marco G. Alves
    Pages 73-74
  9. Back Matter
    Pages 75-98

About this book

Introduction

This book is focused on Sertoli cell physiology and its role in the spermatogenic event. These cells, known as “nurse cells”, are essential for the normal development of germ cells by offering not only physical support and creating an immune-privileged environment, but also for providing nutritional support. The presence of Sertoli cells promotes the establishment of the appropriate microenvironment so that spermatogenesis may occur. Spermatogenesis maintenance in vivo is highly dependent on the metabolic cooperation established between Sertoli cells and developing germ cells. For many years this metabolic cooperation between testicular cells has been disregarded, but recent advances have highlighted the relevance of these processes for male fertility. Thus, the understanding of the functioning and regulation of these metabolic processes is a crucial step to identify key mechanisms associated with Sertoli cell (dys)function and to enlighten their influence on male fertility.

Keywords

Blood-testis barrier Cell Metabolism Male Reproductive Biology Male fertility Sertoli cells Spermatogenesis

Authors and affiliations

  • Pedro F. Oliveira
    • 1
  • Marco G. Alves
    • 2
  1. 1.CICS—UBI—Health Sciences Research CentreUniversity of Beira InteriorCovilhaPortugal
  2. 2.CICS—UBI—Health Sciences Research CentreUniversity of Beira InteriorCovilhaPortugal

Bibliographic information

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