Life Extension

Lessons from Drosophila

  • Alexander M. Vaiserman
  • Alexey A. Moskalev
  • Elena G. Pasyukova

Part of the Healthy Ageing and Longevity book series (HAL, volume 3)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Genetic Regulation of Longevity

    1. Front Matter
      Pages 1-1
    2. Elena Pasyukova, Alexander Symonenko, Natalia Roshina, Mikhail Trostnikov, Ekaterina Veselkina, Olga Rybina
      Pages 3-37
    3. Alexey A. Moskalev, Ekaterina N. Proshkina, Mikhail V. Shaposhnikov
      Pages 39-65
    4. Oleksandr M. Maistrenko, Svitlana V. Serga, Alexander M. Vaiserman, Iryna A. Kozeretska
      Pages 83-104
  3. Drosophila Models for Aging-Associated Diseases

    1. Front Matter
      Pages 105-105
    2. Melissa J. Puppa, Fabio Demontis
      Pages 107-126
    3. Alyson Sujkowski, Robert Wessells
      Pages 127-150
    4. Christofi Theodoulakis, Yiorgos Apidianakis
      Pages 151-189
    5. Lorena de Mena, Pedro Fernandez-Funez, Diego E. Rincon-Limas
      Pages 191-211
  4. Life-Extending Treatments

    1. Front Matter
      Pages 227-227
    2. Lee Shin-Hae, Min Kyung-Jin
      Pages 229-244
    3. Alexander M. Vaiserman, Elena G. Pasyukova
      Pages 245-264
    4. Khatchik Muradian
      Pages 285-299
  5. Back Matter
    Pages 349-353

About this book


This book looks at aging through research on Drosophila, the fruit fly that is one of the most widely used model organisms in biogerontology. Work in model organisms can expand the theoretical knowledge of aging: it yields valuable insight into the molecular and cellular processes that underlie aging process, and it can perhaps provide new therapeutic targets for the treatment of age-related disorders in humans.

Drosophila models have been developed for a large variety of aging-related processes and diseases, and this book provides readers with an overview of current research on the use of the Drosophila model to understand the genetic, molecular and physiological mechanisms that underlie the aging process. Themes of healthspan, life extension and longevity-associated genes emerge in this collation of international research on Drosophila that is of relevance to geriatrics and gerontology, animal genetics and genomics, and biomedicine.

This fascinating, illustrated book will be of interest to a wide audience, ranging from academic researchers to the general reader.



Aging Drosophila Healthspan Life extension Longevity-associated genes

Editors and affiliations

  • Alexander M. Vaiserman
    • 1
  • Alexey A. Moskalev
    • 2
  • Elena G. Pasyukova
    • 3
  1. 1.Laboratory of EpigeneticsInstitute of GerontologyKievUkraine
  2. 2.Laboratory of Molecular Radiobiology and GerontologyInstitute of Biology of Komi Science Center of Ural Branch of RASSyktyvkarRussia
  3. 3.Laboratory of Genome VariationInstitute of Molecular Genetics of RASMoscowRussia

Bibliographic information

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