Biomaterials in Regenerative Medicine and the Immune System

  • Laura┬áSantambrogio

Table of contents

  1. Front Matter
    Pages i-ix
  2. Isabella Pallotta, Emily A. Wrona, Bruce Sun, Donald O. Freytes
    Pages 1-15
  3. Tony Yu, Valerie J. Tutwiler, Kara Spiller
    Pages 17-34
  4. Kaitlyn Sadtler, Franck Housseau, Drew Pardoll, Jennifer H. Elisseeff
    Pages 35-51
  5. Anirban Sen Gupta
    Pages 113-137
  6. Evelyn Bracho-Sanchez, Jamal S. Lewis, Benjamin G. Keselowsky
    Pages 139-156
  7. Alex Schudel, Michael C. Bellavia, Susan N. Thomas
    Pages 157-170
  8. Fnu Apoorva, Ankur Singh
    Pages 171-192
  9. Matthew Levy, Deborah Palliser
    Pages 193-207
  10. Viness Pillay, Pradeep Kumar, Yahya E. Choonara
    Pages 209-223
  11. Tzu-Hua Lin, Jukka Pajarinen, Florence Loi, Taishi Sato, Changchun Fan, Zhenyu Yao et al.
    Pages 225-256
  12. Back Matter
    Pages 279-280

About this book


The generation of tridimensional tissues, assembled from scaffolding materials populated with biologically functional cells, is the great challenge and hope of tissue bioengineering and regenerative medicine. The generation of biomaterials capable of harnessing the immune system has been particularly successful. This book provides a comprehensive view of how immune cells can be manipulated to suppresses inflammation, deliver vaccines, fight cancer cells, promote tissue regeneration or inhibit blood clotting and bacterial infections by functionally engineered biomaterials. However, long-lived polymers, such as those employed in orthopedic surgery or vascular stents, can often induce an immune reaction to their basic components.  As a result, this book is also an important step towards coming to understand how to manipulate biomaterials to optimize their beneficial effects and downplay detrimental immune responses.

Dr. Santambrogio is Professor of Pathology, Microbiology and Immunology and Orthopedic Surgery at the Albert Einstein College of Medicine. She received her M.D. from the University of Perugia and her Ph.D. from the University of Padua in Italy. She received her postdoctoral training at NYU and Harvard Medical School. One of the focuses of the research in her laboratory is the understanding of the immune responses to implanted biomaterials.



Biomaterials Inflammation Macrophages Regenerative medicine immunology

Editors and affiliations

  • Laura┬áSantambrogio
    • 1
  1. 1.Albert Einstein College of MedicineBronxUSA

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